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Duncan laboratory, University of Colorado Health Sciences Center, develops and applies proteomics methods to problems in clinical research. Activities include quantification and characterization of proteins (including their modifications) in complex biological tissues and fluids.
The CPC is funded by the NIH/NHLBI to analyze protein variations caused by oxidative stress, a condition influenced by smoking, exposure to ionizing radiation, and other lifestyle and environmental processes. Includes related links at Boston, Massachusetts.
William Lane's lab at Harvard provides expertise and core technologies in proteomics for the Harvard community and researchers worldwide. These include mass spectrometry, high sensitivity peptide sequencing and protein identification, microcapillary and microbore HPLC separations of chemical or proteolytic digestions.
The Proteomics Center will bring together faculty with highly regarded research programs in vascular biology, hematopoiesis, and hypertension with faculty who are leaders in designing the cell permeable synthetic biomolecule delivery systems that hold enormous promise for developing entirely new strategies for disease treatment.
The center's mission is to apply state-of-the-art methods and to develop new approaches and techniques to investigate the proteomics of adaptation to ischemia and hypoxia, a biological process of general relevance to heart, lung and blood diseases.
With a special focus on structural proteomics to determine experimental structures of all proteins, the proteomics group is fully equipped with state-of-the-art instrumentation for high throughput cloning, protein production and characterization, as well as structure determination by both NMR spectroscopic and X-ray crystallographic methods.
The core serves the greater university community, University of North Carolina - Chapel Hill, by providing a resource for training, education, and consultation in modern proteomic techniques.
Experts from different sectors of basic or clinical fields. Includes human 2-D PAGE databases for proteome analysis in health and disease, galleries protocols and related links.