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Research > Chapter 9038



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Modulation of the human IgE response


Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds


Modulation of the human nociceptive reflex by cyclic movements

Modulation of the humoral immune response by placental secretory factors

Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition




Modulation of the hypothalamo-pituitary-adrenocortical responses to cytokines in the rat by lipocortin 1 and glucocorticoids: A role for lipocortin 1 in the feedback inhibition of CRF-41 release?

Modulation of the hypoxic ventilatory response by Ca2+-dependent and Ca2+-independent protein kinase C in the dorsocaudal brainstem of conscious rats

Modulation of the immune response by changing neuromediator systems activity under stress

Modulation of the immune response by cysteine and cysteine derivatives

Modulation of the immune response of BALB/C mice against Leishmania major by Imuvert




Modulation of the immunophenotype of ovarian cancer cells by N,N-dimethylformamide and transforming growth factor-beta-1

Modulation of the immunostimulating effect of autologous tumor vaccine by anti-TGF-beta antibody and interferon-alpha on murine MBT-2 bladder cancer

Modulation of the immunosuppressive activity of CKS-17, a synthetic retroviral envelope peptide, by muramyl dipeptide



Modulation of the in vitro cytotoxicity of doxorubicin in multidrug resistant cells with and without P-glycoprotein expression

Modulation of the in vivo actions of morphine by the mixed CCK-A/B receptor antagonist PD 142898

Modulation of the in vivo antibody response by a benzodiazepine inverse agonist (DMCM) administered centrally of peripherally

Modulation of the in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3: III. Enhancement by RP-3 treatment of the anti-sheep red blood cell plaque-forming cell response in rats


Modulation of the incidence of hamster pulmonary endocrine cell hyperplasia by unilateral collapse of the lung

Modulation of the indications of adjuvant hormonal treatment by tamoxifen in T1T2/N0N1 breast carcinomas. Preliminary results of a multicentric study including 695 cases

Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774


Modulation of the inflammatory effects of inhaled ozone in rats by subcutaneous prolactin-secreting, pituitary-derived tumors

Modulation of the inflammatory response by corticotropin-releasing factor


Modulation of the inhibitory effect of phenylethylamine on spontaneous motor activity in mice by CPP (racemic)-3-(2-carboxypiperazin-4-YL)-propyl-1-phosphonic acid



Modulation of the insulin-like growth factor system by chronic alcohol feeding

Modulation of the insulin-like growth factor-I system by N-(4-hydroxyphenyl)-retinamide in human breast cancer cell lines


Modulation of the insulinotropic action of glibenclamide and glimepiride by nutrient secretagogues in pancreatic islets from normoglycemic and hyperglycemic rats


Modulation of the intestinal microflora by the non-absorbable antibiotic vancomycin leads to a reduction of the tumor load in liver and spleen in a leukemic rat model

Modulation of the intracellular Ca-2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells

Modulation of the intracellular and H-3-histamine receptors and chemically-induced seizures in mice

Modulation of the intracellular calcium and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol-anchored protein sgp-60


Modulation of the intracellular survival of Brucella abortus by tuftsin and muramyl dipeptide

Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice


Modulation of the inwardly rectifying potassium channel IRK1 by the m1 muscarinic receptor

Modulation of the isoprenaline-induced membrane hyperpolarization of mouse skeletal muscle cells

Modulation of the jaw jerk reflex by the sympathetic nervous system



Modulation of the kinetics of the initial leukocyte migration into renal allografts by 16, 16-dimethyl PGE-2

Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase

Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin


Modulation of the levels of ouabain-like compound by central catecholamine neurons in rats



Modulation of the locomotor response to amphetamine by corticosterone

Modulation of the low-affinity IgE Fc receptor (FC-epsilon-RII/CD23) by leishmania chagasi


Modulation of the maize plasma membrane proton nitrate symport carrier by nitrate

Modulation of the malignant phenotype and the immunological response of tumor cells by Sophora flavescens Ait (AF-7)


Modulation of the measuring range of a radioimmunoassay using an organic water two phase system

Modulation of the mechanically evoked perioral reflex during active force dynamics in young adults

Modulation of the megakaryoblastic Dami cell line differentiation by phosphodiesterase inhibitors and imidazo(1,2-a)pyrazine derivatives


Modulation of the metarhodopsin I/metarhodopsin II equilibrium of bovine rhodopsin by ionic strength: Evidence for a surface-charge effect

Modulation of the micturition reflex pathway by intravesical electrical stimulation: An experimental study in the rat

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH: Evidence that the pore open-closed probability is regulated by reversible histidine protonation



Modulation of the mitochondrial permeability transition by nitric oxide


Modulation of the molecular organization and activity of casein kinase 2 by naturally occurring polyamines

Modulation of the multicatalytic proteinase complex by lipids, interconversion and proteolytic processing


Modulation of the mutagenic activity of cigarette smoke, cigarette smoke condensate and benzo (a) pyrene in vitro and in vivo

Modulation of the mutagenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by phenolic compounds

Modulation of the neuraminidase activity of HN protein from Newcastle disease virus by substrate binding and conformational change: Kinetic and thermal denaturation studies

Modulation of the neurofibromatosis type 1 gene product, neurofibromin, during Schwann cell differentiation

Modulation of the neuronal nicotinic acetylcholine receptor channel by imidacloprid and cartap


Modulation of the neuronal response to N-methyl-D-aspartate by slective sigma2 ligands

Modulation of the neurotensin striato-nigral pathway by D1 receptors

Modulation of the nicotinic acetylcholine receptor channels by spermine in Xenopus muscle cell culture

Modulation of the organization of the extracellular matrix and production of collagen by interferon gamma in three-dimensional cultures of normal and scleroderma fibroblasts

Modulation of the osteoclast Ca-2+ receptor by extracellular protons: Possible linkage between Ca-2+ sensing and extracellular acidification

Modulation of the oxidation-reduction potential of the flavin in lipoamide dehydrogenase from Escherichia coli by alteration of a nearby charged residue, K53R


Modulation of the pharmacokinetics of 5'-deoxy-5-fluorouridine and 5-fluorouracil in rats by oral co-administration of acyclothymidine

Modulation of the phenotype and function of bovine afferent lymph cells during infection with Trypanosoma congolense

Modulation of the phenotype in dominant erythropoietic protoporphyria by a low expression of the normal ferrochelatase allele

Modulation of the phenotypic diversity of sickle cell anemia

Modulation of the phosphate-starvation response in Escherichia coli by genetic manipulation of the polyphosphate pathways

Modulation of the phospholipase C activity in rat brain cortical membranes by simultaneous activation of distinct monoaminergic and cholinergic muscarinic receptors

Modulation of the phosphorylation of glucose-regulated protein, GRP78, by transformation and inhibition of glycosylation


Modulation of the pituitary and basomedial hypothalamic lysyl-aminopeptidase activities by beta-estradiol and/or an aqueous extract of Physalis alkekengi fruits

Modulation of the plasma cholesteryl ester transfer by stachybotramide


Modulation of the plasma membrane electron transfer system in root cells of Limnobium stoloniferum by external pH

Modulation of the plasminogen activation system by inflammatory cytokines in human colon carcinoma cells

Modulation of the plasminogen activation system in murine macrophages

Modulation of the plasminogen activator cascade during enhanced epidermal proliferation in vivo

Modulation of the plasminogen activator/plasmin system in rat liver regenerating by recruitment of oval cells

Modulation of the platelet-derived growth-factor-induced calcium signal by extracellular/intracellular pH in Syrian hamster embryo cells: Implications for the role of calcium in mitogenic signalling

Modulation of the positional specificity of lecithin-cholesterol acyltransferase by the acyl group composition of its phosphatidylcholine substrate: Role of the sn-1 acyl group

Modulation of the pressor response elicited by carbachol and electrical stimulation of the amygdala by muscarinic antagonists in conscious rats

Modulation of the production of reactive oxygen species by pre-activated neutrophils by aminoadamantane derivatives

Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen

Modulation of the proliferative response of murine Peyer's patch lymphocytes by different peptides: CCK-8, CGRP, CCK-PZ and VIP: Preliminary results

Modulation of the properties of penicillin G acylase by acyl donor substrates during N-protection of amino compounds

Modulation of the prostaglandin responses of conscious rabbits to the pyrogen polyinosinic:polycytidylic acid by corticotrophin-releasing factor-41

Modulation of the protein kinase C-dependent NADPH oxidase by some fatty acids in human adherent monocytes: Mechanism of action, possible role in atherogenesis

Modulation of the protein kinase CK2 activity by a synthetic peptide corresponding to the N-terminus of its beta regulatory subunit


Modulation of the rat alveolar macrophage respiratory burst by hydroperoxides is calcium dependent

Modulation of the rat hepatic cytochrome P450 composition by long-term streptozotocin-induced insulin-dependent diabetes

Modulation of the rat mesolimbic dopamine pathway by neurokinins

Modulation of the rat suprachiasmatic circadian clock by melatonin in vitro

Modulation of the rat tumor-associated shedding antigen (CE7) and augmentation of immunogenicity by irradiation

Modulation of the rate, enantioselectivity, and substrate specificity of semisynthetic transaminases based on lipid binding proteins using site directed mutagenesis

Modulation of the receptor binding affinity of amphiregulin by modification of its carboxyl terminal tail


Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: Thermodynamic properties and crystal structures of glycine-61 mutants


Modulation of the reflex cardiac response in Protophormia terraenovae to gustatory stimulation

Modulation of the relationship between amylase and chymotrypsinogen secretion in atropine- and MK329-infused rats

Modulation of the release and activity of neuropeptides in the microcirculation

Modulation of the release of adenosine by glucose and chemical hypoxia in cultured renal cells (MDCK line)

Modulation of the release of cytokines and reduction of the shock syndrome induced by anti-CD3 monoclonal antibody in mice by interleukin-10

Modulation of the release of nitric oxide and TNF-alpha in rat macrophages pretreated in vivo with LPS

Modulation of the renal effects of contrast media by endothelium-derived nitric oxide in the rat



Modulation of the resorptive activity of rat osteoclasts by small changes in extracellular pH near the physiological range

Modulation of the respiratory burst activity of Mediterranean sea bass (Dicentrarchus labrax L.) phagocytes by growth hormone and parasitic status

Modulation of the respiratory burst in human neutrophils by isoproterenol and dibutyryl cyclic AMP

Modulation of the respiratory responses to hypoxia and hypercapnia by synaptic input onto caudal hypothalamic neurons

Modulation of the response of a rodent fibrosarcoma to photodynamic therapy by hyperbaric oxygen treatment

Modulation of the retinoic acid and retinoid X receptor signaling pathways in P19 embryonal carcinoma cells by calreticulin


Modulation of the satiety effect of cholecystokinin by estradiol


Modulation of the septal influences on the hippocampal neurons by cholinergic drugs

Modulation of the serine base exchange enzyme activity of rat brain membranes by amphiphilic cations and amphiphilic anions



Modulation of the shedding of a rat tumor-associated antigen by growth regulation and anti-cancer drugs


Modulation of the skeletal muscle ryanodine receptor by endogenous phosphorylation of 160/150-kDa proteins of the sarcoplasmic reticulum

Modulation of the skeletal muscle sodium channel alpha-subunit by the beta-1-subunit

Modulation of the sodium/potassium pump of peripheral nerve-pharmacology manipulation of protein kinase C

Modulation of the spc operon affects growth and protein secretion in Bacillus subtilis


Modulation of the spontaneous G2 phase blockage in Fanconi anemia cells by caffeine: Differences from cells arrested by X-irradiation

Modulation of the stability of a Lac repressor mediated looped complex by temperature and ions: Allosteric regulation by chloride


Modulation of the stimulus effects of morphine by d-Amphetamine

Modulation of the stress response by ethanol in the rat frontal cortex

Modulation of the stress-induced synthesis of hsp27 and alpha-B-crystallin by cyclic AMP in C6 rat glioma cells

Modulation of the stress-induced synthesis of stress proteins by a phorbol ester and okadaic acid

Modulation of the subcellular distribution of calmodulin by melatonin in MDCK cells

Modulation of the substrate specificity of Escherichia coli dimethylsulfoxide reductase

Modulation of the substrate specificity of the mammalian phosphatidylinositol 3-kinase by cholesterol sulfate and sulfatide

Modulation of the suppression efficiency and amino acid identity of an artificial yeast amber isoleucine transfer RNA in Escherichia coli by a G-U pair in the anticodon stem

Modulation of the surface architecture of Gram-negative bacteria by the action of surface polymer:lipid A-core ligase and by determinants of polymer chain length


Modulation of the synaptic drive to respiratory premotor and motor neurons

Modulation of the synthesis and glycosylation of the glucose transporter protein by transforming growth factor-beta-1 in Swiss 3T3 fibroblasts

Modulation of the testicular steroidogenic pathway by cyclosporin A in adult rats pretreated with diethylstilbestrol



Modulation of the tissue reaction to biomaterials. II. The function of T cells in the inflammatory reaction to crosslinked collagen implanted in T-cell-deficient rats


Modulation of the transcellular metabolism of 12(S)HETE by 10-11 reductase activity in cultured rat aortic smooth muscle cells


Modulation of the transcriptional rate of Fc-gamma receptor mRNA in human mononuclear phagocytes

Modulation of the transcripts for tumor necrosis factor-alpha and its receptors in-vivo

Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids


Modulation of the urethral pressure by high-frequency block stimulus in dogs

Modulation of the vacuolar H+-ATPase by adenylates as basis for the transient CO2-dependent acidification of the leaf vacuole upon illumination

Modulation of the vagal bradycardia evoked by stimulation of upper airway receptors by central 5-HT1 receptors in anesthetized rabbits

Modulation of the ventilatory increase at the onset of exercise in humans

Modulation of the voltage-dependent calcium channels of smooth muscle by phosphorylation

Modulation of the xanthine oxidase/xanthine dehydrogenase ratio by reaction of malondialdehyde with NH-2-groups


Modulation of thermal resistance of proteolytic Clostridium botulinum spore by aromatic flavor carbonyls

Modulation of thermoprotection and translational thermotolerance induced by Semliki Forest virus capsid protein

Modulation of thioacetamide-induced hepatocellular necrosis by prostaglandins is associated with novel histologic changes


Modulation of thresholds to acoustical and electrical stimulation of the intact ear in guinea pig by furosemide and noise

Modulation of thrombin and thrombin receptor peptide mitogenicity by human lung mast cell tryptase

Modulation of thrombin-induced platelet aggregation by inhibition of calpain by a synthetic peptide derived from the thiol-protease inhibitory sequence of kininogens and S-(3-nitro-2-pyridinesulfenyl)cysteine

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells

Modulation of thrombospondin receptor expression during HL-60 cell differentiation

Modulation of thrombotic responses in moderately stenosed arteries by cigarette smoking and aspirin ingestion

Modulation of thromboxane receptor activation in rat glomerular mesangial cells


Modulation of thymidine incorporation by kappa-opioid ligands in rat spinal cord-dorsal root ganglion co-cultures

Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA-alpha-2 and peroxisome proliferator-activated receptor: Evidence for different mechanisms of inhibition

Modulation of thyroxine uptake and efflux in vitro by temelastine and phenobarbital in cultured hepatocytes from different species, in relation to toxicological effects on the thyroid gland


Modulation of tissue angiotensinogen gene expression by glucocorticoids, estrogens, and androgens in SHR and WKY rats

Modulation of tissue angiotensinogen gene expression in genetically obese hypertensive rats



Modulation of tissue trace metal concentrations in weaning rats fed different levels of zinc and exposed to oral lead and cadmium

Modulation of tissue-type plasminogen activator by retinoids in rat plasma and tissues

Modulation of topoisomerase activities by tumor necrosis factor

Modulation of toxicity by diet and dietary macronutrient restriction

Modulation of toxicity by dietary and environmental factors

Modulation of toxicity following external beam irradiation preceded by high-dose rate brachytherapy in inoperable oesophageal cancer

Modulation of trained and extinguished stimuli by facilitators and inhibitors

Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helix


Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen


Modulation of transcription factor-DNA interactions by anticancer drugs

Modulation of transcription of rRNA genes by rapamycin

Modulation of transcription of the rat fibronectin gene by cell density




Modulation of transcriptional regulatory properties of p53 by HPV E6

Modulation of transduction gain in light adaptation of retinal rods

Modulation of transferrin receptor expression by dexrazoxane (ICRF-187) via activation of iron regulatory protein

Modulation of transferrin receptor expression by insulin and granulocyte-macrophages colony stimulating factor in AML-193 leukemic cells


Modulation of transferrin secretion by epidermal growth factor in immature rat Sertoli cells in vitro



Modulation of transforming growth factor-beta secretion from malignant glioma cells by interleukin-1-beta

Modulation of transforming growth factor-beta-1 antiproliferative effects on endothelial cells by cysteine, cystine, and N-acetylcysteine

Modulation of transforming growth factor-beta-1 effects by cytokines

Modulation of transforming growth factor-beta-1 stimulated elastin and collagen production and proliferation in porcine vascular smooth muscle cells and skin fibroblasts by basic fibroblast growth factor, transforming growth factor-alpha, and insulin-like growth factor-I

Modulation of transforming growth factor-beta-1-induced internucleosomal DNA fragmentation and c-myc expression by phorbol esters in primary cultures of hepatocytes



Modulation of transient type potassium channel cloned from rat heart


Modulation of transmitter release and of its receptor interaction in the neuromuscular junction

Modulation of transmitter release from the terminals of the locust wing stretch receptor neuron by muscarinic antagonists

Modulation of trehalase activity in Saccharomyces cerevisiae by an intrinsic protein

Modulation of trichosanthin antigenicity by coupling to dextran

Modulation of tritiated flunitrazepam binding by natural and synthetic progestational agents

Modulation of tryptophan hydroxylase activity in vitro by ethanol depends on biopterin cofactor concentration


Modulation of tubuloglomerular feedback responsiveness by extracellular ATP

Modulation of tumor immunogenicity of rat glioma cells by s-Myc expression: Eradication of rat gliomas in vivo


Modulation of tumor necrosis factor-alpha release by anisoosmolarity and betaine in rat liver macrophages (Kupffer cells)

Modulation of tumor necrosis factor-alpha, interleukin-1-beta, interleukin-6, interleukin-8, and granulocyte/macrophage colony-stimulating factor expression in human monocytes by an endogenous anxiogenic benzodiazepine ligand, triakontatetraneuropeptide: Evidence for a role of prostaglandins

Modulation of tumor necrosis factor-induced increase in renal (LLC-PK-1) transepithelial permeability

Modulation of tumor progression by anti-idiotypic antibodies of angiogenic factors

Modulation of tumor-associated antigen expression on human pancreatic and prostate carcinoma cells in vitro by alpha- and gamma-interferons


Modulation of tumour marker CA-125 expression in cultured ovarian carcinoma cells

Modulation of two cloned potassium channels by 1-alkanols demonstrates different cutoffs

Modulation of two forms of tumor necrosis factor receptors and their cellular response by soluble receptors and their monoclonal antibodies


Modulation of type VII collagen (anchoring fibril) expression by retinoids in human skin cells

Modulation of type-1 plasminogen activator inhibitor-induced vitronectin multimerization


Modulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase after inhibiting monoamine oxidase-A

Modulation of tyrosine kinase activity has multiple actions on insulin release from the pancreatic beta-cells: Studies with Lavendustin A

Modulation of ultraviolet light mutational hotspots by cellular stress

Modulation of unitary glutamatergic synapses by neurotrophin-4/5 or brain-derived neurothrophic factor in hippocampal microcultures Presynaptic enhancement depends on pre-established paired-pulse facilitation

Modulation of upper extremity motoneurone excitability following noxious finger tip stimulation in man: A study with transcranial magnetic stimulation

Modulation of uptake of heme by rat small intestinal mucosa in iron deficiency

Modulation of urethane (ethyl carbamate) carcinogenicity by ethyl alcohol: A review

Modulation of urinary bladder function by sex hormones in streptozotocin-diabetic rats

Modulation of urinary mutagenicity by genetically determined carcinogen metabolism in smokers

Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma

Modulation of urokinase-type plasminogen activator expression by the wild-type and mutated p53 tumor suppressor gene

Modulation of urokinase-type plasminogen activator gene expression by inflammatory cytokines in human pre-B lymphoma cell line RC-K8


Modulation of uterine resistance artery lumen diameter by calcium and G protein activation during pregnancy

Modulation of vagal actions on heart rate produced by inhibition of nitric oxide synthase in the anaesthetized ferret

Modulation of vascular ATP diphosphohydrolase by fatty acids

Modulation of vascular K-ATP channels in hypothyroidism

Modulation of vascular calcium channel activity in response to acute volume expansion in rats

Modulation of vascular contractile response to alpha-1- and alpha-2-adrenergic and neuropeptide Y receptor stimulation in rats with ischaemic heart failure

Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: Role in vasodilatation

Modulation of vascular function by diet and exercise



Modulation of vascular reactivity by vasoactive peptides in aortic rings from hypercholesterolemic rabbits

Modulation of vascular tone and glycerol levels measured by in situ microdialysis in rat adipose tissue

Modulation of vascular tone in renal microcirculation by erythrocytes: Role of EDRF

Modulation of vasoactive intestinal peptide pulmonary relaxation by NO in tracheally superfused guinea pigs lungs

Modulation of vasoactive intestinal polypeptide (VIP)-mediated relaxation by nitric oxide and prostanoids in the rabbit corpus cavernosum

Modulation of vasoconstriction by clopidogrel and ticlopidine

Modulation of vasoconstriction by endothelium-derived nitric oxide: The influence of vascular disease

Modulation of vasoconstriction by insulin

Modulation of vasodilatation to levcromakalim by adenosine analogues in the rabbit ear: An explanation for hypoxic augmentation

Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: A comparison with pinacidil, sodium nitroprusside and verapamil

Modulation of vasopressin actions of human platelets by plasma adenosine and theophylline: Gender differences

Modulation of vasorelaxant responses to potassium channel openers by basal nitric oxide in the rat isolated superior mesenteric arterial bed

Modulation of vastus medialis mononeuronal excitability by sciatic nerve afferents

Modulation of ventilatory control during exercise




Modulation of very late activation-2 laminin receptor function in breast cancer metastasis


Modulation of vesicle shedding in 8701 BC human breast carcinoma cells

Modulation of vestibulospinal reflexes through microinjection of GABAergic agents in the dorsal pontine tegmentum of decerebrate cats

Modulation of vestibulospinal reflexes through microinjection of an alpha-1-adrenergic antagonist in the dorsal pontine tegmentum of decerebrate cats

Modulation of vigilance and behavioral activation by alpha-1 adrenoceptors in the rat

Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells

Modulation of vinblastine pharmacology in human tumor cells by meso-nordihydroguaiaretic acid

Modulation of vinblastine resistance with cyclosporine: A phase I study


Modulation of virulence factor expression by pathogen target cell contact

Modulation of virus-induced delayed-type hypersensitivity by plasmid DNA encoding the cytokine interleukin-10

Modulation of visually evoked responses in units of the ventral lateral geniculate nucleus of the rat by somatic stimuli


Modulation of vitellogenin II gene by estradiol and progesterone in the Japanese quail

Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: A structure-function analysis

Modulation of volitional ethanol intake in the rat by central delta-opioid receptors

Modulation of voltage-activated calcium currents by pain-inducing agents in a dorsal root ganglion neuronal line, F-11

Modulation of voltage-activated ion currents on identified neurons of Helix pomatia L. by interleukin-1

Modulation of voltage-dependent Ca-2+ conductance by changing Cl- concentration in rat lactotrophs




Modulation of voltage-dependent calcium current in Helix aspersa buccal neurones by serotonin and protein kinase C activators

Modulation of voltage-dependent inactivation of the inwardly rectifying K+ channel by chloramine-T





Modulation of vomiting by the medullary midline

Modulation of water and solute transport following food restriction in the colons of the levant vole (Microtus guenteri) and the mouse (Mus musculus)

Modulation of water diffusion during gonadotropin-induced ovulation: NMR microscopy of the ovarian follicle


Modulation of wingless signaling by Notch in Drosophila

Modulation of wound healing in Swiss albino mice by different doses of gamma radiation

Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes

Modulation of yeast F-actin structure by a mutation in the nucleotide-binding cleft

Modulation of zeta-protein kinase C by cyclic AMP in PC12 cells occurs through phosphorylation by protein kinase A

Modulation on prostaglandin H synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

Modulation rate detection and discrimination by normal-hearing and hearing-impaired listeners


Modulation transfer function and contrast sensitivity of multizonal refractive multifocal intraocular lenses

Modulation with cytokines of radiation injury: Suggested mechanisms of action


Modulations by taurine of the spontaneous action potentials in right atrial muscles of rats


Modulations in cell-mediated immunity of Mytilus edulis following the 'Sea Empress' oil spill

Modulations in cerebral hemodynamics under three response requirements while solving language-based problems: A transcranial Doppler study

Modulations in hepatic branch-point enzymes involved in isoprenoid biosynthesis upon dietary and drug treatments of rats

Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K-12

Modulations in the immune defences of mussels (Mytilus edulis) from contaminated sites in the UK


Modulations of 92kDa gelatinase B and its inhibitors are associated with HIV-1 infection in human macrophage cultures

Modulations of Elastin Expression and Cell Proliferation by Retinoids in Cultured Vascular Smooth Muscle Cells

Modulations of breast fibroblast and carcinoma cell interactions by a dextran derivative (CMDB7)

Modulations of cytokine expression in pregnant women

Modulations of membrane potential oscillations with drive, calcium overload, ryanodine and caffeine

Modulations of membrane-pyridopurine interactions induced by the nature of their side chain: An NMR study

Modulations of soleus H-reflex induced by acoustic stimulations in man

Modulations of the effector function and cytokine production of human lymphocytes by secreted factors derived from colorectal-carcinoma cells

Modulations of the effects of choline on tobacco cells by a solid medium and a sucrose or phosphate supplementation

Modulative effects of metabolic effectors on benzo(a)pyrene-induced cytotoxicity and mutagenicity in mammalian cells

Modulative role of thiamine in the synaptic transmission in freshwater molluscs



Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7


Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells

Modulators of calcium and potassium channels: Their effects on endothelin-1 binding to cardiac membranes

Modulators of carcinogenesis



Modulators of intracellular metabolism in the treatment of internal ear diseases

Modulators of nitric oxide in porcine endotoxemia: Effects on hepatic oxygen delivery and consumption

Modulators of nucleotide metabolism inhibit HIV replication in lymphoid cells and affect its inhibition by dideoxynucleosides

Modulators of oxidized LDL-induced hyperadhesiveness in human endothelial cells


Modulators of the protein kinase C system influence biliary excretion of cationic drugs

Modulatory action of Helicobacter pylori on histamine release from mast cells and basophils in vitro

Modulatory action of PACAP27 on NMDA receptor channel activity in cultured chick cortical neurons

Modulatory action of arachidonic acid on GABA-A/chloride channel receptor function in adult and aged brain cortex membranes

Modulatory action of dopamine on acetylcholine-responsive striatal and accumbal neurons in awake, unrestrained rats

Modulatory action of epidermal growth factor on differentiated human granulosa lutein cells: Cross-talk between ligand activated receptors for EGF and gonadotropin

Modulatory action of extracellular zinc on the transient potassium current in rat cerebellar granule cells

Modulatory action of kainic acid on the release of endogenous and exogenous glutamate from rat brain cortical synaptosomes

Modulatory action of progesterone and progesterone antagonists on hypothalamic: Pituitary function

Modulatory actions of Mystus gonadotropin on gamma-BHC-induced histological changes, cholesterol, and sex steroid levels in Heteropneustes fossilis



Modulatory actions of estradiol and progesterone on phorbol ester-stimulated LH secretion from cultured rat pituitary cells

Modulatory actions of gamma aminobutyric acid (GABA) on GABA type a receptor subunit expression and function


Modulatory actions of ovine luteinizing hormone-releasing hormone and Mystus gonadotropin on gamma-BHC-induced Changes in lipid levels in the freshwater catfish, Heteropneustes fossilis

Modulatory actions of progesterone on gonadotropin-releasing hormone-induced arachidonic acid liberation from perifused rat pituitary cells

Modulatory and direct effects of propofol on recombinant GABAA receptors expressed in Xenopus oocytes: Influence of alpha- and gamma2-subunits

Modulatory drug action in an allosteric Markow model of ion channel behavior: Biphasic effects with access-limiting binding to either a stimulatory or an inhibitory site

Modulatory effect of 4 beta-phorbol 12-myristate 13-acetate (PMA) on carbachol-induced Ca-2+ mobilization in rat parotid acinar cells

Modulatory effect of 8-iso-PGE-2 on platelets

Modulatory effect of L-NAME, a specific nitric oxide synthase (NOS) inhibitor, on stress-induced changes in plasma adrenocorticotropin hormone (ACTH) and corticosterone levels in rats: Physiological significance of stress-induced NOS activation in hypothalamic-pituitary-adrenal axis


Modulatory effect of N-acetyl-L-cysteine on the HIV-1 multiplication in chronically and acutely infected cell lines

Modulatory effect of acupuncture on the cardiovascular system: A cross-over study

Modulatory effect of agents active in the presynaptic dopaminergic system on the striatal dopamine transporter


Modulatory effect of antidepressants on peripheral-type benzodiazepine receptors

Modulatory effect of arachidonate 5-lipoxygenation on glomerular cell proliferation in nephrotoxic serum nephritis

Modulatory effect of areca nut on the action of mace (Myristica fragrans, Houtt) on the hepatic detoxification system in mice

Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R, 2R-diaminocyclohexaneplatinum-(IV) complexes

Modulatory effect of bradykinin on noradrenaline release in isolated atria from normal and B2 knockout transgenic mice

Modulatory effect of bradykinin on the release of noradrenaline from rat isolated atria

Modulatory effect of cyclic AMP on calcium fluxes in FRTL-5 cells

Modulatory effect of cytokines on glycolipid expression of human glioma cell line U118MG: Changeable response and gradual loss of sensitivity to cytokines of glioma cells in culture

Modulatory effect of dalargin on glutamatergic synaptic transmission in the ampullae of Lorenzini of skates

Modulatory effect of dehydrated cabbage on the detoxifying enzymes of rats with a carcinogen treatment


Modulatory effect of erythrocytes on the platelet reactivity to collagen in IDDM patients

Modulatory effect of esophageal intraluminal mechanical and chemical stressors on salivary prostaglandin E-2 in humans

Modulatory effect of extracellular Mg-2+ ions on K+ and Ca-2+ currents of capillary endothelial cells from rat brain

Modulatory effect of hyperthermia on hepatic microsomal cytochrome P450 in mice

Modulatory effect of insulin on release of calcium from human fibroblasts by angiotensin II

Modulatory effect of interleukin-10 on the production of platelet-activating factor and superoxide anions by human leukocytes

Modulatory effect of learning and memory on honey bee brain acetylcholinesterase activity

Modulatory effect of maternal serum on xenobiotic metabolizing activity of placental explants: Modification by cigarette smoking

Modulatory effect of neuropeptide Y on acetylcholine-induced oedema and vasoconstriction in isolated perfused lungs of rabbit

Modulatory effect of nonesterified fatty acids on structure and binding characteristics of estrogen receptor from MCF-7 human breast cancer cells

Modulatory effect of piperine on benzo(a)pyrene cytotoxicity and DNA adduct formation in V-79 lung fibroblast cells

Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons

Modulatory effect of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) on macrophage functions in BALB/c mice: I. Potentiation of macrophage bactericidal activity

Modulatory effect of potassium-diffusion membrane potential on proton ATPase hydrolytic activity in higher plant plasma membranes at various temperatures

Modulatory effect of prolactin on the resting and mitogen-induced activity of T, B, and NK lymphocytes


Modulatory effect of sepia shell extract on activity of glucose-6-phosphatase and alanine amino transferase in diabetic mice

Modulatory effect of sodium butyrate on AluI-induced chromosomal aberrations in CHO cells

Modulatory effect of steroid hormones on GnRH-induced LH secretion by cultured rat pituitary cells

Modulatory effect of tamoxifen and ICI 182,780 on adriamycin resistance in MCF-7 human breast-cancer cells

Modulatory effect of tempol on toxicity and antitumor activity of 6-mercaptopurine and on P450 cytochrome level

Modulatory effect of the neurotensin on the parasympathetic regulation of the cardiac rhythm



Modulatory effects of (Met-5)-enkephalin on interleukin-1-beta secretion from microglia in mixed brain cell cultures



Modulatory effects of L-DOPA on D2 dopamine receptors in rat striatum, measured using in vivo microdialysis and PET

Modulatory effects of NMDA on phosphoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R-ACPD in neonatal rat cerebral cortex

Modulatory effects of Novobiocin, actinomycin D, and caffeine on heat shock protection against induction of chromatid aberrations by maleic hydrazide in Hordeum vulgare

Modulatory effects of SMS 201-995 on anti-CD3-induced apoptosis in thymus

Modulatory effects of a synthetic steroid (tibolone) and estradiol on spontaneous and GH-RH-induced GH secretion in postmenopausal women


Modulatory effects of achatin I, an Achatina endogenous neuroactive peptide, on responses to 5-hydroxytryptamine

Modulatory effects of acute ethanol on metabotropic glutamate responses in cultured Purkinje neurons

Modulatory effects of adenosine on Porichthys luminescence


Modulatory effects of antifilarial drugs ivermectin, CGP 6140 and CGP 20376 on the oxidative burst of eosinophilic granulocytes


Modulatory effects of biogenic amines on adipokinetic hormone secretion from locust corpora cardiaca in vitro

Modulatory effects of ceruloplasmin on lymphocytes, neutrophils and monocytes of patients with altered immune status

Modulatory effects of ddC and AZT/ddC combination on murine and human immune responses


Modulatory effects of diltiazem on inotropic responses to amrinone on rabbit isolated atria

Modulatory effects of eicosanoids on mesangial cell growth in response to immune injury


Modulatory effects of endothelin on baroreflex activation in the nucleus of the solitary tract

Modulatory effects of endothelin-1 on purinergic and adrenergic components of sympathetically-mediated contractile activity of rabbit saphenous artery

Modulatory effects of essential oils from spices on the formation of DNA adduct by a aflatoxin B-1 in vitro

Modulatory effects of gamma-hydroxybutyric acid on a GABAA receptor from crayfish muscle

Modulatory effects of gonadorelin on GABA-induced depolarization and GABA-activated current in rat spinal ganglion neurons

Modulatory effects of hen egg-white lysozyme on immune response in mice

Modulatory effects of human cytomegalovirus infection on malignant properties of cancer cells

Modulatory effects of human donor bone marrow cells on allogeneic cellular immune responses

Modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices

Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay

Modulatory effects of morphine, U-50488H and 1,3-di(2-tolyl) guanidine on cocaine-like discriminative stimulus in the rat using two-choice discrete-trial avoidance paradigm

Modulatory effects of neurosteroid of the function of GABA-A receptor chloride ion channels

Modulatory effects of peroxovanadates on insulin receptor binding

Modulatory effects of plasma and serum on T lymphocyte activation: Distinctive patterns for different mitogens

Modulatory effects of polycyclic aromatic hydrocarbons on the mutagenicity of 1-nitropyrene: A structure-activity relationship study



Modulatory effects of staphylococcal superantigen TSST-1 on IgE synthesis in atopic dermatitis

Modulatory effects of substrate specificity of independent mutations at the serine-939/941 position in predicted transmembrane domain 11 of P-glycoproteins

Modulatory effects of tamoxifen and recombinant human alpha-interferon on doxorubicin resistance

Modulatory effects of testosterone on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

Modulatory effects of the colonic milieu on neutrophil oxidative burst: A possible pathogenic mechanism of ulcerative colitis

Modulatory effects of total glucosides of paeony on B lymphocyte proliferation and interleukin 1 production

Modulatory effects of vasopressin on glucose and protein metabolism during food-restriction stress


Modulatory function on autologous myeloid progenitor cells of clonal T-lymphocytes following autologous bone marrow transplantation

Modulatory impact of acid and pepsin on esophageal hydrophobicity in humans

Modulatory influence of alcoholic extract of Ocimum leaves on carcinogen-metabolizing enzyme activities and reduced glutathione levels in mouse

Modulatory influence of arecanut on antioxidant 2(3)-tert-butyl-4-hydroxy anisole-induced hepatic detoxification system and antioxidant defence mechanism in mice

Modulatory influence of arecanut on the mouse hepatic xenobiotic detoxication system and skin papillomagenesis

Modulatory influence of arecoline on the phytic acid-altered hepatic biotransformation system enzymes, sulfhydryl content and lipid peroxidation in a murine system

Modulatory influence of camphor on the activities of hepatic carcinogen metabolizing enzymes and the levels of hepatic and extrahepatic reduced glutathione in mice

Modulatory influence of chlorophyllin on the mouse skin papillomagenesis and xenobiotic detoxication system

Modulatory influence of oral contraceptives on mammary growth pattern of normal and ovariectomised mice

Modulatory influence of sandalwood oil on mouse hepatic glutathione-S-transferase activity and acid soluble sulphydryl level

Modulatory influence of the oral contraceptive pill, ovral, on 3-methylcholanthrene-induced carcinogenesis in the uterus of mouse

Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation (HNCS) in fibromyalgia patients and healthy subjects

Modulatory influences of estrogen and progesterone on cervical dysplasia in mice model system

Modulatory mechanism of ACTH on insulin secretion: Effect on cytosolic Ca-2+, membrane potential and Ca2+-ATPase activity

Modulatory mechanisms at a primitive neuromuscular synapse: Membrane currents, transmitter release and modulation by transmitters in a Cnidarian motor neuron

Modulatory mechanisms in Pavlovian conditioning

Modulatory mechanisms in the isolated internally perfused ventricle of the whelk Busycon canaliculatum

Modulatory mechanisms of cyclic AMP-stimulated steroid content in rat brain cortex

Modulatory potential of iron chelation therapy on nitric oxide formation in cerebral malaria

Modulatory potential of smokeless tobacco on the garlic, mace or black mustard-altered hepatic detoxication system enzymes, sulfhydryl content and lipid peroxidation in murine system

Modulatory role of 1,25 dihydroxyvitamin D-3 on pancreatic islet insulin release via the cyclic AMP pathway in the rat

Modulatory role of 5-HT-3 receptors in gastric function and ethanol-induced mucosal damage in rat stomachs

Modulatory role of D-1 and D-2 dopamine receptor subtypes in nociception in mice

Modulatory role of acetylcholine in the rat pineal gland

Modulatory role of catecholamines in the transsynaptic expression of c-fos in the rat medial prefrontal cortex induced by disinhibition of the mediodorsal thalamus: A study employing microdialysis and immunohistochemistry


Modulatory role of dopamine on excitatory amino acid receptors


Modulatory role of endothelial and nonendothelial nitric oxide in 5-hydroxytryptamine-induced contraction in cerebral arteries after subarachnoid hemorrhage

Modulatory role of endothelial calcium level in vascular tension of canine depolarized coronary arteries

Modulatory role of endothelium-derived relaxing factors on the response to vasoconstrictors and flow-pressure curve in the isolated perfused rat kidney


Modulatory role of epidermal growth factor in follicle-stimulating hormone-induced DNA synthesis in cultured rat granulosa cells

Modulatory role of estrogens and progestins on growth hormone episodic release in women with hypothalamic amenorrhea

Modulatory role of lipoprotein oxidation on platelet-vessel wall interactions

Modulatory role of magnesium on the contractile response of rat aorta to several agonists in normal and calcium-free medium

Modulatory role of nitric oxide on superoxide-dependent luminol chemiluminescence


Modulatory role of protein kinase C on the signal transduction pathway utilized by platelet-activating factor in eosinophil activation

Modulatory role of protein tyrosine kinase activation in the receptor-induced contractions of the bovine cerebral artery


Modulatory treatment of NMDA receptors in neonatal rats affects cognitive behavior in adult age

Module performance of anion-exchange porous hollow-fiber membranes for high-speed protein recovery

Module swaps between related translocator proteins pIV-f1, pIV-IKe and PuID: Identification of a specificity domain

Module-module interactions in the cell binding region of fibronectin: Stability, flexibility and specificity