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Research > Chapter 10042



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2B4 functions as a co-receptor in human NK cell activation


2B4 stimulation of YT cells induces natural killer cell cytolytic function and invasiveness


2B4-mediated activation of human natural killer cells

2B4: An NK cell activating receptor with unique specificity and signal transduction mechanism

2D 1H and 13C NMR evidence for stereoselective formation of a new bond C-N, C-S or C-C in the reaction of ivalin acetate with substituted pyrimidines

2D 1H and 13C NMR in the conformation of 4-aryl derivatives of thieno(3,2-c)pyridines

2D JPRESS of human prostates using an endorectal receiver coil

2D NMR analysis of highly restricted internal rotation in 2-methylthio-3H-4-p-bromophenyl)-7-((ortho- and para-substituted)-phenylthio)-1,5-benzodiazepines

2D NMR study on solution structure of natural product 3'-methoxy puerarin

2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors



2D calculation method based on composite beam theory for the determination of local homogenised stiffnesses of long bones

2D conformationally sampled pharmacophore: A ligand-based pharmacophore to differentiate delta opioid agonists from antagonists



2D multislice and 3D MRI sequences are often-equally sensitive



2D simulation of transport and degradation in the river Rhine


2D-FASE MRCP for pediatrics with congenital biliary dilatation: Usefulness of non-breath-hold one-shot MRCP

2D-IR correlation analysis of deteriorative process of traditional Chinese medicine 'Qing Kai Ling' injection


2D-NMR: General aspects

2D-QSAR in hydroxamic acid derivatives as peptide deformylase inhibitors and antibacterial agents

2D-finite element analyses and histomorphology of lag screws with and without a biconcave washer

2D-hyperfine sublevel correlation spectroscopy of tyrosyl radicals

2D-spatial/2D-spectral spectroscopic imaging of intracerebral gliomas in rat brain

2DE image research on character and regularity of cardiac valve atresia

2E4 (Kaptin): A novel actin-associated protein from human blood platelets found in lamellipodia and the tips of the stereocilia of the inner ear

2E4/kaptin (KPTN): A candidate gene for the hearing loss locus, DFNA4

2F1 antigen, the mouse homolog of the rat mast cell function-associated antigen, is a lectin-like type II transmembrane receptor expressed by natural killer cells

2H NMR studies of a myristoylated peptide in neutral and acidic phospholipid bicelles

2H magnetic relaxation of 2H2O absorbed by wool

2H, 13C, and 15N kinetic isotope effects on the reaction of the ammonia-rescued K258A mutant of aspartate aminotransferase

2H- and 13C-labelled tracers compared for kinetic studies of ascorbic acid metabolism in man: A factor analytical approach

2H-NMR comparative study of phosphocholine group conformation in bilayers composed of diacyl and dialkyl phosphatidylcholines

2H-Pyran-2-ones as synthons for (E)-alpha,beta-didehydromino acid derivatives

2H-azirine 3-phosphonates: A new class of chiral iminodienophiles. Asymmetric synthesis of quaternary piperidine phosphonates

2H/1H and 13C/12C isotope ratios of trans-anethole using gas chromatography-isotope ratio mass spectrometry

2H/1H ratio analysis of flavor compounds by on-line gas chromatography pyrolysis isotope ratio mass spectrometry (HRGC-P-IRMS): Benzaldehyde

2H/1H ratio analysis of flavor compounds by on-line gas chromatography-pyrolysis-isotope ratio mass spectrometry (HRGC-P-IRMS): Citral


2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF

2MHz ultrasound enhances t-PA-mediated thrombolysis: Comparison of continuous versus pulsed ultrasound and standing versus travelling acoustic waves

2P1, a novel male mouse cDNA specifically expressed during meiosis

2R,4R-4-aminopyrrolidine-2,4-dicarboxylate (APDC) attenuates cortical EPSPs

2S albumin from buckwheat (Fagopyrum esculentum Moench) seeds


2The morphEffect of septal lesions on male song and aggression in the colonial zebra finch (Taeniopygia guttata) and the territorial field sparrow (Spizella pusilla)

2a-(4-(tetrahydropyridoindol-2-yl)butyl)tetrahydrobenzindole derivatives: New selective antagonists of the 5-hydroxytryptamine7 receptor

2alpha-(3-Hydroxypropyl)- and 2alpha-(3-hydroxypropoxy)-1alpha,25-dihydroxyvitamin D3 accessible to vitamin D receptor mutant related to hereditary vitamin D-resistant rickets

2beta-Carbomethoxy-3beta-(4- and 2-(18F)fluoromethylphenyl)tropanes: Specific probes for in vivo quantification of central dopamine transporter sites

2n + n hybridization of apomictic Paspalum dilatatum with diploid Paspalum species

2n gametes in Solanum Tuberosum dihaploids


2nd Annual Meeting of the Federation of Clinical Immunology Societies, Washington, DC, USA, april 15-17, 1999


2nd BioValley Tissue Engineering Symposium, Freiburg, Germany, November 25-27, 1999


2nd Congress of the International Shoulder Group, Calgary, Canada, August 15-16, 1999

2nd European Congress of Pharmacology (Drugs against disease to improve quality of life: Gateway to the 21st Century through EPHAR (Federation of the European Pharmacological Societies), (Budapest, Hungary; July 3-7, 1999)

2nd Giessen-Marburg-Goettinger Transport Colloquium (Rauischolzhausen, Germany; January 21-22, 1999)




2nd International Conference on the Biology and Chemistry of Peroxynitrite (Heraklion, Crete, Greece; May 15-20, 1999)

2nd International Congress of the Vascular Access Society, London, England, UK, May 30-June 1, 2001

2nd International Congress on Cardiovascular Disease, Kosice, Slovakia, April 25-27, 2002


2nd International Congress on Psoriasis: From Gene to Clinic, London, UK, December 2-4, 1999

2nd International Forum on Progressive Endocrinology (I'FOPE), Tokyo, Japan, February 1-2, 2002

2nd International Meeting on Rapid Responses to Steroid Hormones, Denver, CO, USA, June 16-18, 2001

2nd International Society of Pediatric Oncology (SIOP) Asia Conference and 6th National Conference of Pediatric Hematology-Oncology and Parents Meeting, New Delhi, India, November 22-24, 2002

2nd International Symposium of the German Network for Competence in Rheumatology, Bamberg, Germany, March 8-10, 2001

2nd International Symposium on Obesity and Hypertension, Berlin, Germany, October 25-27, 2001

2nd International Workshop on Musculoskeletal Interactions, Delphi, Greece, May 18-21, 2000

2nd Joint Meeting of the International Cytokine Society and the International Society for Interferon and Cytokine Research (Jerusalem, Israel; October 25-30, 1998)


2nd Shanghai International Pediatric Symposium, Shanghai, China, October 29-November 1, 2002

2nd Sino-European Congress of laboratory medicine: Strategies for laboratory diagnostics in medicine

2nd Symposium on Cytokines and Apoptosis in the Cardiovascular System (Halle, germany; February 24-26, 1999)

2nd Workshop Chlamydiae in cattle and pigs and the zoonotic potential, Jena, Germany, September 24-25, 2002


2nd to 4th digit ratio and a universal mean for prenatal testosterone in homosexual men

2nd to 4th digit ratio and offspring sex ratio

2nd-trimester maternal serum marker results are not altered by delayed analysis

3 Beta-hydroxysteroid dehydrogenase isomerase (3beta-HSD) activity in the rat sciatic nerve: Kinetic analysis and regulation by steroids


3 R study: Renal outcome in renal ischemia: Revascularisation or medical treatment





3' Polymorphisms of ETS1 are associated with different clinical phenotypes in SLE

3' RACE walking along a large cDNA employing tiered suppression PCR

3' Splicing variants of ret receptor tyrosine kinase are differentially expressed in mouse embryos and in adult mice





3'' BCR recombines with IGL locus in BCR-ABL-positive Philadelphia-negative chronic myeloid leukemia





3',5'-Cyclic adenosine monophosphate regulates expression of synaptotagmin in neonatal sympathetic ganglia in vitro

3',5'-Cyclic nucleotide phosphodiesterases class III: Members, structure, and catalytic mechanism

3',5'-Di-C-beta-glucopyranosylphloretin, a flavonoid characteristic of the genus Fortunella



3'-(N-hydroxyimino)-2',3-dideoxynucleosides and their derivatives: Synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analogues

3'-5' Exonuclease of Klenow fragment: Role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting

3'-5' Exonucleolytic activity of DNA polymerases: Structural features that allow kinetic discrimination between ribo- and deoxyribonucleotide residues

3'-Aminoadenosine-5'-uronamides: Discovery of the first highly selective agonist at the human adenosine A3 receptor

3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells



3'-Azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

3'-Azido-3'-deoxythymidine reduces the rate of transferrin receptor endocytosis in K562 cells


3'-Azidoabscisic acid as a photoaffinity reagent for abscisic acid binding proteins



3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase


3'-Deoxy-3'-C-trifluoromethyl nucleosides: Synthesis and antiviral evaluation

3'-Deoxyribonucleosides and their derivatives as anti-amoebic agents


3'-End processing of precursor M1 RNA by the N-terminal half of RNase E



3'-Fluorine-substitution in 3'-fluorocarbocyclic oxetanocin A augments the drug's inhibition of HHV-6B propagation in chronically infected cultures

3'-Methoxy-4'-nitroflavone, a reported aryl hydrocarbon receptor antagonist, enhances Cyp1a1 transcription by a dioxin responsive element-dependent mechanism



3'-Oligonucleotides conjugation via chemoselective oxime bond formation

3'-Phosphoadenosine 5'-phosphosulfate binding site of flavonol 3-sulfotransferase studied by affinity chromatography and 31P NMR


3'-Phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling


3'-Terminal RNA secondary structures are important for accumulation of tomato bushy stunt virus DI RNAs





3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT

3'-beta-ethynyl and 2'-deoxy-3'-beta-ethynyl adenosines: First 3'-beta-branched-adenosines substrates of adenosine deaminase

3'-deoxy-3'-fluoro analogues of 2-5A core trimers: Their effect on the lytic activity of human NK lymphocytes


3'-end conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: Synthesis and anti-ras activity in radiation-resistant cells

3'-end modification of the adenoviral VA1 gene affects its expression in human cells: Consequences for the design of chimeric VA1 RNA ribozymes


3'-terminal region of gene repB of Lactobacillus plasmid pLF1311 is extended because of the lack of the stop codon of precursor gene

3'Sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro

3'UTRs of glutathione peroxidases differentially affect selenium-dependent mRNA stability and selenocysteine incorporation efficiency

3'azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)


3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents


3,3',4,4'-tetrachlorobiphenyl oxidation in fish, bird and reptile species: Relationship to cytochrome P450 1A inactivation and reactive oxygen production

3,3'-Dideoxytrehaloses via dimerisation of 2-hydroxyglycal esters


3,3'-Diindolylmethane, a major condensation product of indole-3-carbinol, is a potent estrogen in the rainbow trout


3,3a-Dihydropyrano(4,3,2-de)quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors

3,4 Methylenedioxymethamphetamine (ecstasy) impairs eight-arm radial maze performance and arm entry pattern in rats


3,4-Diaryl-5-hydroxyfuranones: Highly selective inhibitors of cyclooxygenase-2 with aqueous solubility



3,4-Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats

3,4-Dihydro-1-isoquinolinamines: A novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency

3,4-Dihydro-2(1H)-quinolinone as a novel antidepressant drug: Synthesis and pharmacology of 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone and its derivatives


3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential

3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans

3,4-Dihydroxyphenylacetaldehyde and hydrogen peroxide generate a hydroxyl radical: Possible role in Parkinson's disease pathogenesis

3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells


3,4-Dipyranosyl-1,2,5-oxadiazole 2-oxides: Synthesis and X-ray structure

3,4-Methylenedioxymetamphetamine (ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices

3,4-Methylenedioxymethamphetamine (Ecstasy) induces apoptosis of cultured rat liver cells

3,4-Methylenedioxymethamphetamine (Ecstasy) stimulates the expression of alpha1(I) procollagen mRNA in hepatic stellate cells




3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) -induced egr-1 mRNA in rat brain: Pharmacological manipulation

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) and driving impairment




3,4-anhydro-1,2-O-isopropylidene-beta-D-tagatopyranose and 4,5-anhydro-1,2-O-isopropylidene-beta-D-fructopyranose

3,4-dideoxyglucosone-3-ene (3,4-DGE): A cytotoxic glucose degradation product in fluids for peritoneal dialysis

3,4-dihydro-3,4,6-trimethyl-2H,8H-pyrano-(3,2g)-1,3-benzoxazin-2,8-dione, a potential fluorogenic reporter group reagent for esterases: Synthesis and interaction with chymotrypsin


3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P2 elements for selectivity

3,4-homoadamantadiene: Generation and regioselective (2+2) cycloaddition of a novel tricyclic bridgehead allene

3,4-methylenedioxymethamphetamine (MDMA) abuse markedly inhibits acetylcholinesterase activity and induces severe oxidative damage and lipoperoxidative damage

3,4-methylenedioxymethamphetamine (MDMA) modulates cortical and limbic brain activity as measured by (H215O)-PET in healthy humans



3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat

3,4-methylenedioxymethamphetamine (ecstasy)-induced hepatotoxicity: Effect on cytosolic calcium signals in isolated hepatocytes


3,4-seco-lupanes and other constituents from Platypodium elegans

3,5,3'-Triiodothyronine (T3) and 3',5'-diiodothyrone (T2) have short-term effects on lipid metabolism in a teleost Anabas testudineus (Bloch): Evidence from enzyme activities

3,5,3'-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity

3,5,3'-triiodothyronine administered to rat dams during lactation increases milk yield and triglyceride concentration and hastens pups growth

3,5,3'-triiodothyronine deprivation affects phenotype and intracellular (Ca2+)i of human cardiomyocytes in culture

3,5,6-Trisubstituted naphthostyrils as CDK2 inhibitors


3,5-Bis(trifluoromethyl)pyrazoles: A novel class of NFAT transcription factor regulator

3,5-DHPG influences behavioral effects of baclofen in rats

3,5-Di-t-butyl-4-hydroxyanisole (DTBHA) activation of rat skeletal muscle sarcoplasmic reticulum Ca2+-ATPase

3,5-Diacetyl-1,4-dihydropyridines: Synthesis and MDR reversal in tumor cells

3,5-Dibenzoyl-1,4-dihydropyridines: Synthesis and MDR reversal in tumor cells


3,5-dimethoxy-3-(1,1-dimethylprop-2-enyl)-3,4-dihydropsoralen-4-one: An unusual furanocoumarin derivative from Halfordia kendack

3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation

3,6-Fluorescein diphosphate: A sensitive fluorogenic and chromogenic substrate for protein tyrosine phosphatases

3,7-Dimethylguanine, a new purine from a Philippine sponge Zyzzya fuliginosa

3,7-Disubstituted-1,2,3,4-tetrahydroisoquinolines display remarkable potency and selectivity as inhibitors of phenylethanolamine N-methyltransferase versus the alpha2-adrenoceptor

3,8-Diazabicyclo-(3.2.1)-octane derivatives as analogues of ambasilide, a Class III antiarrhythmic agent


3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)-pyridine: A potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity

3-(123I)Iodo-L-alpha-methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells

3-(123I)Iodo-alpha-methyl-L-tyrosine: Uptake mechanisms and clinical applications

3-(123I)iodo-alpha-methyl-L-tyrosine transport and 4F2 antigen expression in human glioma cells

3-(15-Hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one and its effect on neuropeptide secretion

3-(1H-pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A


3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: Synthesis and evaluation as CFTR activators

3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: A study on the 2-carbamoylvinyl chain modification

3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site

3-(3'-fluorenyl-9'-oxo)-L-alanine: A novel photoreactive conformationally constrained amino acid

3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase

3-(3-(piperidin-1-yl)propyl)indoles as highly selective h5-HT1D receptor agonists


3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) causes Akt phosphorylation and morphological changes in intracellular organellae in cultured rat astrocytes

3-(4-((Benzyl(methyl)amino)methyl)-phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: A dual function lead for Alzheimer's disease therapy

3-(4-(4-nitrophenil)piperazin-1-il)-2-quinoxalinecarbonitrile derivatives as antileucemic agents

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures

3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors

3-(4-Methyl-3-pentenyl)-2(5H)-furanone, alpha,alpha-acariolide and 4-(4-methyl-3-pentenyl)-2(5H)-furanone, alpha,beta-acariolide: New monoterpene lactones from the astigmatid mites, Schwiebea araujoae and Rhizoglyphus sp. (Astigmata: Acaridae)

3-(4-fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT2A receptor antagonists

3-(4-piperidinyl)- and 3-(8-aza-bicyclo(3.2.1)oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT2A antagonists

3-(Arylacetylamino)-N-methylbenzamides: A novel class of selective anti-Helicobacter pylori agents

3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth

3-(Iodoacetamido)-benzoylurea: A novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells

3-(alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-alkyl-N-arylbenzamides: Potent, non-peptidic agonists of both the mu and delta opioid receptors

3-(piperazinylpropyl)indoles: Selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents

3-0 Methylglucose absorption in vivo correlates with nutrient absorption and intestinal surface area in experimental short bowel syndrome

3-Acetylpyridine reduces tongue protrusion force but does not abolish lick rhythm in the rat

3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors

3-Acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid as novel vanilloid receptor agonists

3-Alkyl- and 3-aryl-(7-oxo-7h-furo(3,2-g)chromen-5-yl)alkanoic acids as inhibitors of leukotriene B4 biosynthesis

3-Alkyl- and 3-aryl-7H-furo(3,2-g)-1-benzopyran-7-ones: Synthesis, photoreactivity, and fluorescence properties

3-Alkyl-(5,5'-diphenyl)imidazolidinediones as new cannabinoid receptor ligands

3-Alkylamino-pyrido(4,3-e)-1,2,4-thiadiazine 1,1-dioxides as potent KATP-channel activators: Structural study and influence of stereochemistry

3-Amidinophenylalanine-based inhibitors of urokinase

3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons

3-Amino- and 5-aminopyrazoles with anticonvulsant activity

3-Amino-1,4-dimethyl-5H-pyrido(4,3-b)indole (Trp-P-1) induces apoptosis in rat splenocytes and thymocytes by different mechanisms

3-Amino-1,4-dimethyl-5H-pyrido(4,3-b)indole (Trp-P-1) induces caspase-dependent apoptosis in mononuclear cells

3-Amino-1,4-dimethyl-5H-pyrido(4,3-b)indole (Trp-P-1) is incorporated into rat splenocytes, thymocytes, and hepatocytes through monoamine transporters and induces apoptosis

3-Amino-2-piperidones as constrained pseudopeptides: Preparation of a new Ser-Leu surrogate

3-Amino-4-sulfonylpyridinone acetamide and related pyridothiadiazine thrombin inhibitors

3-Amino-5-hydroxybenzoic acid in antibiotic biosynthesis. XI. Biological origins and semisynthesis of thionaphthomycins, and the structures of naphthomycins I and J

3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet

3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes


3-Aryl pyrazolo(4,3-d)pyrimidine derivatives: Nonpeptide CRF-1 antagonists

3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists

3-Arylpiperidines as potentiators of existing antibacterial agents

3-Azido-3-deoxy-glycopyranoside derivatives as scaffolds for the synthesis of carbohydrate-based universal pharmacophore mapping libraries

3-Benzamido, ureido and thioureidoimidazo(1,2-a)pyridine derivatives as potential antiviral agents

3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo

3-Bromopyrazolo(3,4-d)pyrimidine 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides: Modified DNA constituents with an unusually rigid sugar N-conformation


3-Carboxamido analogues of morphine and naltrexone: Synthesis and opioid receptor binding properties


3-Carboxy-cis,cis-muconate lactonizing enzyme from Neurospora crassa: MAD phasing with 80 selenomethionines

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) as a direct-acting teratogen in micromass in vitro tests

3-Chloro-DL-alanine resistance by L-methionine-alpha-deamino-gamma-mercaptomethane-lyase activity

3-Chlorophenol elimination upon excitation of dilute iron(III) solution: Evidence for the only involvement of Fe(OH)2+


3-Cloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a rat thyroid gland carcinogen, does not affect serum levels of TSH and thyroid hormones

3-Cyano-4,6-disubstituted-2(1H)-imino or oxopyridines: New antineoplastic agents with high selectivity towards leukemia cell lines

3-Cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: Synthesis and initial structure-activity relationships

3-D AE visualization of bone-cement fatigue locations

3-D Golgi and image analysis of the olfactory tubercle in schizophrenia

3-D MRI assessment of regional left ventricular systolic wall stress in patients with reperfused MI

3-D QSAR studies on new dibenzyltin(IV) anticancer agents by comparative molecular field analysis (CoMFA)

3-D US frame positioning using speckle decorrelation and image registration

3-D analysis of vascular and capsular invasion in thyroid follicular carcinoma

3-D baroclinic numerical simulation of the South China Sea I. Upper circulation

3-D breast ultrasound segmentation using active contour model

3-D characterization of ganglion cells of the terminal nerve plexus of rat atrioventricular junction

3-D color video microscopy of intact plants: A new method for measuring shape and growth

3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption

3-D eye movement analysis

3-D in vitro model of early skeletal muscle development


3-D portal image analysis in clinical practice: An evaluation of 2-D and 3-D analysis techniques as applied to 30 prostate cancer patients

3-D power Doppler cerebral angiography in neonates and young infants: Comparison with 2-D power Doppler angiography

3-D reconstructed magnetic resonance imaging in localization of subdural EEG electrodes. Case illustration

3-D reconstruction from tomographic data using 2-D active contours


3-D structural modeling of humic acids through experimental characterization, computer assisted structure elucidation and atomistic simulations. 1. Chelsea soil humic acid

3-D surface reconstruction of multiple sclerosis lesions using spherical harmonics

3-D ultrasound and color Doppler flow imaging for study in ureter cyst

3-D ultrasound quantification of neonatal cerebral ventricles in different head positions


3-D-QSAR CoMFA and CoMSIA studies on tetrahydrofuroyl-L-phenylalanine derivatives as VLA-4 antagonists

3-D-QSAR analysis of N-(3-acyloxy-2-benzylpropyl)-N'-dihydroxytetrahydrobenzazepine and tetrahydroisoquinoline and N-(3-acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl) thioureas analogues as potent vanilloid receptor ligands

3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT4 receptor



3-Deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice

3-Deazauridine triggers dose-dependent apoptosis in myeloid leukemia cells and enhances retinoic acid-induced granulocytic differentiation of HL-60 cells

3-Deoxy-1beta,20-dihydroxyecdysone from the leaves of Diploclisia glaucescens

3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth



3-Deoxyclocinnamox: The first high-affinity, nonpeptide mu-opioid antagonist lacking a phenolic hydroxyl group

3-Deoxyglucosone: Metabolism, analysis, biological activity, and clinical implication

3-Deoxypentosulose: An alpha-dicarbonyl compound predominating in nonenzymatic browning of oligosaccharides in aqueous solution

3-Dimensional analysis of cleft palate casts

3-Dimensional colour power angiography for staging human placental development


3-Dimensional imaging of collagen using second harmonic generation

3-Dimensional organization of the N-terminal vinculin head fragment


3-Dimensional visualization of lesions in rat brain using magnetic resonance imaging microscopy

3-FG as substrate for investigating flux through the polyol pathway in dog lens by 19F-NMR spectroscopy


3-Formylcyclopent-3-enyl- and 3-carboxycyclopentylglycine derivatives: A new stereocontrolled approach via retro-aldol or retro-Claisen reactions

3-Geranyl-4-hydroxy-5-(3'-methyl-2'-butenyl)benzoic acid as an anti-inflammatory compound from Myrsine seguinii

3-Heteroaryl 3,4-dihydro-4-oxo-1,2,3-benzotriazines: Synthesis, characterization, and antibacterial evaluation

3-Heteroaryl-2-pyridones: Benzodiazepine site ligands with functional selectivity for alpha2/alpha3-subtypes of human GABAA receptor-ion channels



3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation

3-Hydroxy-3-methylbutyrate and 2-oxoisocaproate affect body composition and cholesterol concentration in rabbits


3-Hydroxy-3-methylglutaric aciduria presenting with Reye like syndrome: Report of one case


3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase





3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: A nested case-control study

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats


3-Hydroxy-3-methylglutaryl coenzyme A reductase is sterol-dependently cleaved by cathepsin L-type cysteine protease in the isolated endoplasmic reticulum

3-Hydroxy-3-methylglutaryl coenzyme a reductase activity in liver of athymic mice with or without an implanted human carcinoma



3-Hydroxy-3-methylglutaryl-CoA synthase: Participation of invariant acidic residues in formation of the acetyl-S-enzyme reaction intermediate

3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis

3-Hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain

3-Hydroxy-3-methylglutaryl-coenzyme A synthase reaction intermediates: Detection of a covalent tetrahedral adduct by differential isotope shift 13C nuclear magnetic resonance spectroscopy


3-Hydroxy-4,5-dimethyl-2(5H)-furanone (sotolon) causing an off-flavor: Elucidation of its formation pathways during storage of citrus soft drinks

3-Hydroxy-4,5-dimethyl-2(5H)-furanone: A key odorant of the typical aroma of oxidative aged Port wine


3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631

3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gamma

3-Hydroxyanthranilic acid-derived compounds formed through electrochemical oxidation


3-Hydroxyglutaric acid induces oxidative stress and decreases the antioxidant defenses in cerebral cortex of young rats


3-Hydroxykynurenine as a substrate/activator for mushroom tyrosinase



3-Hydroxyquinuclidinium derivatives: Synthesis of compounds and inhibition of acetylcholinesterase

3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor

3-Isobutyl-1-methylxanthine (IBMX) sensitizes cardiac myocytes to anoxia

3-Isobutyl-1-methylxanthine inhibits basal mu-opioid receptor phosphorylation and reverses acute morphine tolerance and dependence in mice

3-Keto-9-O-substituted oxime derivatives of 6-O-methyl erythromycin A synthesis and in vitro activity


3-Methyl-5-hydroxy-5-trichloromethyl-1H-1-pyrazolcarboxyamide induces antinociception


3-Methylcholanthrene activates human immunodeficiency virus type 1 replication via aryl hydrocarbon receptor

3-Methylcholanthrene increases phorbol 12-myristate 13-acetate-induced respiratory burst activity and intracellular calcium levels in common carp (Cyprinus carpio L) macrophages

3-Methylcholanthrene inhibits lymphocyte proliferation and increases intracellular calcium levels in common carp (Cyprinus carpio L)




3-Methyleneoxindole: An affinity label of glutathione S-transferase pi which targets tryptophan 38





3-Methylglutaconic aciduria type III in a non-Iraqi-Jewish kindred: Clinical and molecular findings

3-Methylindole alters both olfactory and trigeminal nasal mucosal potentials in rats

3-Morpholinosydnonimine (SIN-1) and K+ channels in smooth muscle cells of the rabbit and guinea pig carotid arteries


3-Nitrocoumarin is an efficient inhibitor of budding yeast phospholipase-C

3-Nitropropionic acid increases frataxin expression in human lymphoblasts and in transgenic rat PC12 cells

3-Nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: Insights into Huntington's disease

3-Nitropropionic acid induces a spectrum of Huntington's disease-like neuropathology in rat striatum

3-Nitropropionic acid induces cell death and mitochondrial dysfunction in rat corticostriatal slice cultures

3-Nitropropionic acid neurotoxicity in hippocampal slice cultures: Developmental and regional vulnerability and dependency on glucose

3-Nitropropionic acid neurotoxicity in organotypic striatal and corticostriatal slice cultures is dependent on glucose and glutamate


3-Nitropropionic acid preconditioning ameliorates delayed neurological deterioration and infarction after transient focal cerebral ischemia in gerbils


3-Nitropropionic acid: An astrocyte-sparing neurotoxin in vitro

3-Nitrotyrosine immunoreactivity in olfactory receptor neurons of patients with Alzheimer's disease: Implications for impaired odor sensitivity

3-Nitrotyrosine in atherosclerotic blood vessels


3-O-desacyl monophosphoryl lipid A derivatives: Synthesis and immunostimulant activities

3-O-methyl-D-galactose residues in lycophyte primary cell walls

3-O-methyldobutamine, a major metabolite of dobutamine in humans

3-O-methylfluorescein phosphate as a fluorescent substrate for plasma membrane Ca2+-ATPase

3-O-methylquercetin more selectively in phosphodiesterase subtype 3

3-O-substituted benzyl pyridazinone derivatives as COX inhibitors


3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents

3-Phenyl-5-methyl-2H,5H-furan-2-ones: Tuning antifungal activity by varying substituents on the phenyl ring




3-Phosphoinositides modulate cyclic nucleotide signaling in olfactory receptor neurons

3-Phosphono-2-(N-cyanoimino)thiazolidine derivatives, new phosphorylating agents for alcohols

3-Pyrroline containing arylacetamides: A novel series of remarkably selective kappa-agonists

3-Pyrrolines are mechanism-based inactivators of the quinone-dependent amine oxidases but only substrates of the flavin-dependent amine oxidases

3-Substituted analogues of remantadine: Synthesis and antiherpetic activity in culture of vero cells


3-Ureidopropionate contributes to the neuropathology of 3-ureidopropionase deficiency and severe propionic aciduria: A hypothesis

3-Way principal component analysis applied to the evaluation of water quality of underground waters in the area of Siracusa


3-acetoxy group of genuine AKBA (acetyl-11-keto-beta-boswellic acid) is alpha-configurated

3-acetyl-5-acylpyridin-2(1H)-ones and 3-acetyl-7,8-dihydro-2,5(1H,6H)-quinolinediones: Synthesis, cardiotonic activity and computational studies

3-acetylaltholactone and related styryl-lactones, mitochondrial respiratory chain inhibitors

3-alkyl-6-chloro-2-pyrones: Selective inhibitors of pancreatic cholesterol esterase

3-alkylamino-4H-pyrido(2,3-e)-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: Design, synthesis, and pharmacological evaluation

3-alpha-chloro-imperialine, a potent blocker of cholinergic presynaptic modulation of glutamatergic afferents in the rat neostriatum

3-amino-5-phenoxythiophenes: Syntheses and structure-function studies of a novel class of inhibitors of cellular L-triiodothyronine uptake

3-aminobenzamide and 3-aminobenzoic acid, tags for capillary electrophoresis of complex carbohydrates with laser-induced fluorescent detection

3-aminopyrrolidinone farnesyltransferase inhibitors: Design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency

3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

3-aryl(1,2,4)triazino(4,3-alpha)benzimidazol-4(10H)-ones: A new class of selective A1 adenosine receptor antagonists

3-aryl-(1,2,4)triazino(4,3-a)benzimidazol-4(10H)-ones: Tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands

3-aryl-2-quinolone derivatives: Synthesis and characterization of in vitro and in vivo antitumor effects with emphasis on a new therapeutical target connected with cell migration

3-aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors

3-bromo-7-nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs maternal aggression and citrulline immunoreactivity in prairie voles

3-bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: Potential markers for eosinophil-dependent tissue injury in vivo



3-dehydroecdysone secretion by the molting gland of the cockroach, Periplaneta americana (L.)


3-deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli. Model of binding of phosphoenolpyruvate and D-arabinose-5-phosphate

3-deoxyglucosone and AGEs in uremic complications: Inactivation of glutathione peroxidase by 3-deoxyglucosone

3-desoxyanthocyanidins from Arrabidaea chica

3-dimensional volume rendered computerized tomography for preoperative evaluation and intraoperative treatment of patients undergoing nephron sparing surgery

3-ethyl-3-methylmaleimide in Tokyo Bay sediments providing the first evidence for its formation from chlorophylls in the present photic and oxygenic zone




3-hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene



3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats

3-hydroxy-4-methyl-5-pentyl-2-iminopyrrolidine: A potent and highly selective inducible nitric oxide synthase inhibitor

3-hydroxybenzoate:Coenzyme A ligase from cell cultures of Centaurium erythraea: Isolation and characterization

3-hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction

3-hydroxykynurenine potentiates quinolinate but not NMDA toxicity in the rat striatum

3-hydroxylysine, a potential marker for studying radical-induced protein oxidation

3-imidazolylmethylaminophenylsulfonyltetrahydroquinolines, a novel series of farnesyltransferase inhibitors

3-ketosteroid,DELTA1-dehydrogenase of Rhodococcus rhodochrous: Sequencing of the genomic DNA and hyperexpression, purification, and characterization of the recombinant enzyme

3-m-bromoacetylamino benzoic acid ethyl ester: A new cancericidal agent that activates the apoptotic pathway through caspase-9

3-mercapto-2-methylpentan-1-ol, a new powerful aroma compound

3-methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member



3-methyladenine-DNA glycosylase I from Escherichia coli-Computer modeling and supporting experimental evidence

3-methyladenine-DNA glycosylase II: The crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition




3-methylthiopropionaldehyde as precursor of dimethyl trisulfide in aged beers

3-monoterpenyl-2,4-dioxygenated quinoline alkaloids from the aerial parts of Halfordia kendack

3-month formulation of goserelin acetate ('Zoladex' 10.8-mg depot) in advanced prostate cancer: Results from an Italian, open, multicenter trial

3-morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: A critical role for p21ras-MAPK-p19ARF pathway

3-nitro-2-pyridyl glycoside as donor for chemical glycosylation and its application to chemoenzymatic synthesis of oligosaccharide


3-nitropropionic acid induces ischemic tolerance in gerbil hippocampus in vivo

3-nitrotyrosine butyl ester: A novel derivative to assess tyrosine nitration in rat plasma by liquid chromatography-tandem mass spectrometry detection


3-p-toluoyl-2-(4'-(3-diethylaminopropoxy)-phenyl)-benzofuran and 2-(4'-(3-diethylaminopropoxy)-phenyl)-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of beta-amyloid peptide

3-phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: Synthesis and biological activity of a novel group of potential antifungal drugs

3-phosphoglycerate dehydrogenase deficiency in a patient with West syndrome

3-pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing

3-pyridylethanolamines: Potent and selective human beta3 adrenergic receptor agonists

3-thia fatty acid treatment, in contrast to eicosapentaenoic acid and starvation, induces gene expression of carnitine palmitoyltransferase-II in rat liver

3-year results of docetaxel-based sequential and combination regimens in the adjuvant therapy of node-positive breast cancer: A pilot study

3. Nachtrag zum Verzeichnis der Kaefer Deutschlands fuer das mittlere und suedliche Niedersachsen, Region Hannover

30 Gy may be an adequate dose in patients with anal cancer treated with excisional biopsy followed by combined-modality therapy

30 Years of experience with York-Mason repair of recto-urinary fistulas

30 ans: Happy birthday RCPG. Le recepteur B2 de la bradykinine: Voie alternative et antiproliferative

30 mm regeneration of rat sciatic nerve along collagen filaments

30 years of MSA-concept: Review and survey of multiple system atrophy




30,000 years of hydrothermal activity at the lost city vent field

30-Day mortality after cardiac operations: A pilot project of the Working Party of Directors of Hospital Cardiology Departments

30-Item General Health Questionnaire in general hospitals: Selecting items using a stepwise hierarchical procedure

30-Item General Health Questionnaire scores in male and female university freshmen


30-day intravenous administration of VRCTC-310-ONCO in rabbits

30-jaehriger Bodybuilder mit septischem Shock und ARDS bei Abusus anabolandrogener Steroide



30th Annual Medical-Scientific Conference of the American Society of Addiction Medicine (New York City, New York, USA; April 19-May 2, 1999)

30th Annual Meeting and 15th Summer School of the Scandinavian Society for Immunology (Lund, Sweden; August 25-29, 1999)


30th Annual Meeting of the American Association of Stratigraphic Palynologists (Woods Hole, Massachusetts, USA; September 14-19, 1997)


30th Annual Meeti