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Research > Chapter 18019
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Mutagenesis of the amino-terminal glycine to alanine in Gs a subunit alters bc-dependent properties and decreases adenylylcyclase activation
Mutagenesis of the c-Carboxyglutamic Acid Domain of Human Factor VII to Generate Maximum Enhancement of the Membrane Contact Site
Mutagenesis of the central hydrophobic cluster in Ab42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities
Mutagenesis of the conserved aspartic acid 443, glutamic acid 478, asparagine 494, and aspartic acid 498 residues in the ribonuclease H domain of p66/p51 human immunodeficiency virus type I reverse transcriptase. Expression and biochemical analysis
Mutagenesis of the conserved residue Glu259 of Gsa demonstrates the importance of interactions between switches 2 and 3 for activation
Mutagenesis of the coxsackie B3 virus 2B/2C cleavage site: determinants of processing efficiency and effects on viral replication
Mutagenesis cysteines metalloregulatory protein MerR metal-bridged dimer activates transcription
Mutagenesis of the gene encoding cytochrome c550 of Paracoccus denitrificans and analysis of the resultant physiological effects
Mutagenesis of the glycosylation site of human ApoCIII. O-linked glycosylation is not required for ApoCIII secretion and lipid binding
Mutagenesis of the human transferrin receptor: two cytoplasmic phenylalanines are required for efficient internalization and a second-site mutation is capable of reverting an internalization-defective phenotype
Mutagenesis of the iron-regulatory element further defines a role for RNA secondary structure in the regulation of ferritin and transferrin receptor expression
Mutagenesis of the ligand binding domain of the human retinoic acid receptor a identifies critical residues for 9-cis-retinoic acid binding
Mutagenesis redox-active disulfide mercuric ion reductase - catalysis mutant enzymes restricted flavin redox chemistry
Mutagenesis area env srv SR-A strain Rous sarcoma virus function constructing helper-independent vectors
Mutagenesis of the regulatory domain of rat protein kinase C-h. A molecular basis for restricted histone kinase activity
Mutagenesis of the regulatory subunit (RIIb) of cAMP-dependent protein kinase IIb reveals hydrophobic amino acids that are essential for RIIb dimerization and/or anchoring RIIb to the cytoskeleton
Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit
Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity
Mutagenesis studies of interleukin-8. Identification of a second epitope involved in receptor binding
Mutagenesis studies of the human erythropoietin receptor. Establishment of structure-function relationships
Mutagenesis studies of the phosphorylation sites of recombinant human pyruvate dehydrogenase. Site-specific regulation
Mutagenesis supports water mediated recognition in the trp repressor- operator system
Mutagenesis versus Inhibition in the Efficiency of Extinction of Foot-and-Mouth Disease Virus
Mutagenesis within human FceRIa differentially affects human and murine IgE binding
Mutagenesis, by methylating and ethylating agents, in mutH, mutL, mutS, and uvrD mutants of Salmonella typhimurium LT2
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli
Mutagenic Analysis Invariant Aspartate Residue Chorismate Synthase Supports Its Role Active Site Base
Mutagenic DNA repair genes on plasmids from the 'pre-antibiotic era'
Mutagenic DNA repair in enterobacteria
Mutagenic DNA repair potential Pseudomonas spp., characterization rulABPc operon highly mutable strain Pseudomonas cichcorii 302959
Mutagenic Events Escherichia coli Mammalian Cells Generated Response Acetylaminofluorene-Derived DNA Adducts Positioned Nar I Restriction Enzyme Site
Mutagenic Potential Benzo(a)pyrene-Derived DNA Adducts Positioned Codon 273 Human P53 Gene
Mutagenic Properties 3-(Deoxyguanosin-N2-yl)-2-acetylaminofluorene Persistent Acetylaminofluorene-Derived DNA Adduct Mammalian Cells
Mutagenic Properties 5-Halogenuracils - Correlated Quantum Chemical ab Initio Investigation
Mutagenic Stabilization and/or Disruption of a CD4-Bound State Reveals Distinct Conformations of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein
Mutagenic activity of austocystins- secondary metabolites of Aspergillus ustus
Mutagenic activity heat-induced cholesterol-degradation products
Mutagenic activity of incense smoke in Salmonella typhimurium
Mutagenic activity of the amino derivatives and their hydroxamic acids of nitrobiphenyl ethers
Mutagenic activity of the liquid waste from the production of acetonitrile
Mutagenic analysis of AMP nucleosidase from Escherichia coli. Deletion of a region similar to AMP deaminase and peptide characterization by mass spectrometry
Mutagenic examination receptor contact site interleukin-2 - preparation IL-2 analog increased potency
Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts
Mutagenic analysis of platelet thromboxane receptor cysteines. Roles in ligand binding and receptor-effector coupling
Mutagenic analysis of the a subunit of F1F0 ATP synthase in Escherichia coli: Gln-252 through Tyr-263
Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpolh and dpoli
Mutagenic thermodynamic analyses residual formation subunit tryptophan synthase
Mutagenic influence pesticide (Ekatin) soybean test scheme
Mutagenic effects of plant growth hormones with the Salmonella/microsome test and the SOS chromotest
Mutagenic frequencies of site-specifically located O6-methylguanine in wild-type Escherichia coli and in a strain deficient in ada-methyltransferase
Mutagenic nucleoside analog N4-aminocytidine: metabolism, incorporation into DNA, and mutagenesis in Escherichia coli
Mutagenic potential of sediments from the Grand Calumet River
Mutagenic properties of pirimiphos-methyl in male mice
Mutagenic responses tansy ragwort (Senecio jacobaea) plant, pyrrolizidine alkaloids metabolites goat milk Salmonella/mammalian-microsome mutagenicity test
Mutagenic specificities of four stereoisomeric benzo(c)phenanthrene dihydrodiol epoxides
Mutagenic specificity of N-methyl-N'-nitro-N-nitrosoguanidine in the gpt gene on a chromosome of Chinese hamster ovary cells and of Escherichia coli cells
Mutagenic specificity of a novel T4 DNA polymerase mutant
Mutagenic spectrum resulting DNA damage oxygen radicals
Mutagenic, electrochemical, crystallographic investigation cytochrome b5 oxidation-reduction balance - involvement asparagine-57, serine-64, heme propionate-7
Mutagenicity Acute Toxicity Evaluation 2-Dodecylcyclobutanone
Mutagenicity diagnosis response products aqueous chlorine chlorine dioxide L-tryptophan
Mutagenicity assays of leachate from domestic waste landfills in Japan: the establishment of a protocol for measuring mutagenicity levels of leachate
Mutagenicity of Antineoplastic Drug Residues Treated in Health Care Waste Autoclave
Mutagenicity of Polluted Reservoir Water and Its Reduction by a Pilot-Scale Integrated Biological Treatment Process
Mutagenicity of Tama River sediments
Mutagenicity of air pollutants collected at industrial urban-residential and rural areas
Mutagenicity of drinking well water
Mutagenicity of heavy metals
Mutagenicity materials isolated synthetic rubber
Mutagenicity of nitrohumic acid in Salmonella typhimurium strains
Mutagenicity pyrolyzates natural substances Salmonella typhimurium TA97
Mutagenicity structure oxygen radicals trioses glyoxal derivatives
Mutagenicity of the sunlight-exposed sample of pyrene in Salmonella typhimurium TA98
Mutagenicity volatile q-alkenyl isothiocyanates cyanoepithioalkanes
Mutagenicity studies of size-fractionated oil fly ash in the Ames Salmonella typhimurium assay
Mutagenicity, acute toxicity, and bioaccumulation potential of six chlorinated styrenes
Mutagenicity, carcinogenicity, teratogenicity industrial pollutants (book review)
Mutagenicity, horizons genetic toxicology (book review)
Mutant (DF508) cystic fibrosis transmembrane conductance regulator Cl- channel is functional when retained in endoplasmic reticulum of mammalian cells
Mutant Analysis Reveals a Specific Requirement for Protein P30 in Mycoplasma pneumoniae Gliding Motility
Mutant Caenorhabditis elegans RNA polymerase II with a 20,000-fold reduced sensitivity to a-amanitin
Mutant Chinese hamster ovary cells pleiotropically defective in receptor-mediated endocytosis
Mutant Cu/Zn-Superoxide Dismutase Associated with Amyotrophic Lateral Sclerosis Destabilizes Vascular Endothelial Growth Factor mRNA and Downregulates Its Expression
Mutant Desmocollin-2 Causes Arrhythmogenic Right Ventricular Cardiomyopathy
Mutant GABAA receptor c2-subunit childhood absence epilepsy febrile seizures
Mutant Huntingtin Causes Context-Dependent Neurodegeneration in Mice with Huntington's Disease
Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro
Mutant Huntingtin Promotes the Fibrillogenesis of Wild-type Huntingtin. A Potential Mechanism for Loss of Huntingtin Function in Huntington's Disease
Mutant LexA proteins with an increased rate of in vivo cleavage
Mutant Luciferase Enzymes Fireflies Increased Resistance Benzalkonium Chloride
Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6
Mutant MotB proteins in Escherichia coli
Mutant MyoD Lacking Cdc2 Phosphorylation Sites Delays M-Phase Entry
Mutant Myocilin Nonsecretion In Vivo Is Not Sufficient To Cause Glaucoma
Mutant NDUFV1 subunit mitochondrial complex I leukodystrophy myoclonic epilepsy
Mutant POLG2 Disrupts DNA Polymerase g Subunits and Causes Progressive External Ophthalmoplegia
Mutant PrPSc Conformers Induced by a Synthetic Peptide and Several Prion Strains
Mutant Protein Kinase Cg Found in Spinocerebellar Ataxia Type 14 Is Susceptible to Aggregation and Causes Cell Death
Mutant R1 Proteins from Escherichia coli Class Ia Ribonucleotide Reductase with Altered Responses to dATP Inhibition
Mutant Superoxide Dismutase 1 Forms Aggregates in the Brain Mitochondrial Matrix of Amyotrophic Lateral Sclerosis Mice
Mutant U2 snRNAs Xenopus form altered higher order RNA formation unable enter nucleus
Mutant U5A cells are complemented by an interferon-ab receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster
Mutant Viral Polymerase Transition Virus Error Catastrophe Identifies Critical Site RNA Binding
Mutant a-Latrotoxin (LTXN4C) Does Not Form Pores and Causes Secretion by Receptor Stimulation. This Action Does Not Require Neurexins
Mutant a-synuclein-induced degeneration reduced parkin fly model Parkinson's disease
Mutant aminoacyl-tRNA synthetase compensates mutation major identity determinant tRNA
Mutant examination Prevotella sp. plaA-lacZ fusion protein expression Escherichia coli - support essential function stem-loop
Mutant examination Prevotella sp. plaA|AnlacZ fusion protein expression Escherichia coli - support essential function stem-loop
Mutant and chimeric recombinant plasminogen activators. Production in eukaryotic cells and preliminary characterization
Mutant and wild type human a-synucleins assemble into elongated filaments with distinct morphologies in vitro
Mutant b-spectrin 4 auditory motor neuropathies quivering mice
Mutant cells defective poly(ADP-ribose) synthesis due stable alterations enzyme activity substrate availability
Mutant clone of Chinese hamster ovary cells lacking 3-hydroxy-3-methylglutaryl coenzyme A reductase
Mutant conformation p5Precise epitope mapping filamentous phage epitope library
Mutant farnesyltransferase b subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I b subunit
Mutant genes familial Alzheimer's disease transgenic models
Mutant glycosyltransferase altered glycosylation a-dystroglycan myodystrophy mouse
Mutant hemoglobins (a119-Ala b55-Ser) - functions similar high-altitude respiration geese
Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism
Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition
Mutant isoforms of the anti-Mullerian hormone type II receptor are not expressed at the cell membrane
Mutant isolation gene transfer tools study transport proteins
Mutant isolation and molecular cloning of mre genes, which determine cell shape, sensitivity to mecillinam, and amount of penicillin-binding proteins in Escherichia coli
Mutant l repressors with increased operator affinities reveal new, specific protein-DNA contacts
Mutant lac repressors with new specificities hint at rules for protein-DNA recognition
Mutant membrane protein toxicity
Mutant mice galore
Mutant mice mimic human sickle cell anemia
Mutant mouse lysozyme carrying a minimal T cell epitope of hen egg lysozyme evokes high autoantibody response
Mutant myosin VIIa defective melanosome distribution RPE shaker-1 mice
Mutant of Bacillus species isolated on the basis of protonophore resistance are deficient in fatty acid desaturase activity
Mutant of Escherichia coli K-12 with defective phosphorylation of two periplasmic transport proteins
Mutant of Escherichia coli deficient in osmoregulation of periplasmic oligosaccharide synthesis
Mutant of Salmonella typhimurium LT2 deficient in DNA adenine methylation
Mutant of interleukin 13 with altered reactivity toward interleukin 13 receptors
Mutant of the glutamine transfer RNA gene as UGA suppressor in Escherichia coli
Mutant offspring. Five Forsythia varieties progeny irradiated Forsythia (times) intermedia Lynwood Gold
Mutant p53 Attenuates SMAD-Dependent Transforming Growth Factor b1 (TGF-b1) Signaling Pathway Repressing Expression TGF-b Receptor Type II
Mutant p53 Gain Function Two Mouse Models Li-Fraumeni Syndrome
Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor b1
Mutant presenilin 2 transgenic mice. A large increase in the levels of Ab42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin
Mutant prohead RNAs vitro packaging bacteriophage f29 DNA-gp3
Mutant rho factors increased transcription termination activities. Functional correlations primary secondary polynucleotide binding sites efficiency site-selectivity rho-dependent termination
Mutant rho factors increased transcription termination activities. Identification functional dissection amino acid
Mutant s factor blocks transition between promoter binding and initiation of transcription
Mutant sequences in the rpsL gene of Escherichia coli B/r: mechanistic implications for spontaneous and ultraviolet light mutagenesis
Mutant strain of Bradyrhizobium japonicum with increases symbiotic N2 fixation rates and altered Mo metabolism properties
Mutant subtilisin E with enhanced protease activity obtained by site-directed mutagenesis
Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection
Mutant vitamin D receptors which confer hereditary resistance to 1,25-dihydroxyvitamin D3 in humans are transcriptionally inactive in vitro
Mutant yolk protein lead female sterility Drosophila
Mutant-Selective Thyromimetics Chemical Rescue Thyroid Hormone Receptor Mutants Associated Resistance Thyroid Hormone
Mutants affecting processing of DNA in macronuclear development in Paramecium
Mutants and Intersexual Heterokaryons of Blakeslea trispora for Production of b-Carotene and Lycopene
Mutants revertants avian influenza A virus temperature-sensitive defects nucleoprotein PB2
Mutants xantha albina loci relationship chloroplast biogenesis barley (Hordeum vulgare L.) (book review)
Mutants generated insertion random oligonucleotides active site b-lactamase gene
Mutants in ABC10b, a conserved subunit shared by all three yeast RNA polymerases, specifically affect RNA polymerase I assembly
Mutants in a Small Heat Shock Protein That Affect the Oligomeric State. Analyses and Allele-specific Suppression
Mutants conserved area carboxy-terminus HIV-1 Rev identify functionally important residues exhibit dominant negative phenotype
Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes
Mutants glucose metabolism
Mutants in signal transduction through the T-cell antigen receptor
Mutants in the putative nucleotide-binding region of the plasma membrane Ca2+-pump. A reduction in activity due to slow dephosphorylation
Mutants in trs 120 disrupt traffic from the early endosome to the late Golgi
Mutants of Agrobacterium VirA that activate vir gene expression in the absence of the inducer acetosyringone
Mutants of Arabidopsis deficient in the synthesis of a-linolenate. Biochemical and genetic characterization of the endoplasmic reticulum linoleoyl desaturase
Mutants of Aspergillus nidulans blocked at an early stage of sporulation secrete an unusual metabolite
Mutants Bacillus stearothermophilus defective absorption metabolism acetate
Mutants Bacillus subtilis 168 thermosensitive growth wall teichoic acid synthesis
Mutants Bacillus subtilis defective protein export
Mutants Caenorhabditis elegans form Dauer-like larvae
Mutants of Chinese hamster ovary cells affected in two different microtubule-associated proteins: genetic and biochemical studies
Mutants Circadian-Associated PRR Genes Display New Visible Phenotype Light Responses De-Etiolation Arabidopsis thaliana Seedlings
Mutants Escherichia coli O9:K30 altered synthesis expression capsular K30 antigen
Mutants of Escherichia coli defective for replicative transposition of bacteriophage Mu
Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase
Mutants of Escherichia coli initiator tRNA defective in initiation. Effects of overproduction of methionyl-tRNA transformylase and the initiation factors IF2 and IF3
Mutants Escherichia coli producing pyrroloquinoline quinone
Mutants Escherichia coli specifically deficient respiratory formate dehydrogenase activity
Mutants Escherichia coli altered hydrogenase activity
Mutants of FtsZ Targeting the Protofilament Interface: Effects on Cell Division and GTPase Activity
Mutants of H-ras that interfere with RAS effector function in Saccharomyces cerevisiae
Mutants HLA-A2 examination formation role
Mutants of Neuroserpin That Cause Dementia Accumulate as Polymers within the Endoplasmic Reticulum
Mutants Phosphorylase Altered Recognition Protein Phosphatase-1
Mutants of Plasminogen Activator Inhibitor-1 Designed to Inhibit Neutrophil Elastase and Cathepsin G Are More Effective in Vivo than Their Endogenous Inhibitors
Mutants Pseudomonas facilis defective lithoautotrophy
Mutants of Pseudomonas fluorescens NCIMB 11671 defective in the catabolism of a-pinene
Mutants of Pseudomonas fluorescens deficient in dissimilatory nitrite reduction are also altered in nitric oxide reduction
Mutants of Rab3A analogous to oncogenic ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing
Mutants of S. cerevisiae defective in the maintenance of minichromosomes
Mutants of Saccharomyces cerevisiae defective in sn-1,2-diacylglycerol cholinephosphotransferase. Isolation, characterization, and cloning of the CPT1 gene
Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins
Mutants of Streptococcus faecalis sensitive to alkaline pH lack Na+-ATPase
Mutants Streptococcus gordonii Challis over-producing glucosyltransferase
Mutants Streptococcus pneumoniae temperature-sensitive autolysin
Mutants influenza A reassortant cold-sensitive (cs) temperature-sensitive (ts) - function neuraminidase activity influenza virus infection
Mutants of bakers' yeast producing a large amount of isobutyl alcohol or isoamyl alcohol, flavour components of bread
Mutants of complement component C3 cleaved by the C4-specific C1s protease
Mutants human insulin-like growth factor I reduced affinity type 1 insulin-like growth factor receptor
Mutants of human insulin-like growth factor II with altered affinities for the type 1 and type 2 insulin-like growth factor receptor
Mutants of initiator tRNA that function both as initiations and elongators
Mutants corn (book review)
Mutants pheV Escherichia coli affecting control attenuation pheS, T pheA operons. Two distinct mechanisms de-attenuation
Mutants of single chain interleukin 5 show asymmetric recruitment of receptor a and bc subunits
Mutants of the EcoRI endonuclease with promiscuous substrate specificity implicate residues involved in substrate recognition
Mutants Zinc Ligands Lacticin 481 Synthetase Retain Dehydration Activity Have Impaired Cyclization Activity
Mutants of the membrane-binding region of Semliki Forest virus E2 protein. Cell surface transport and fusogenic activity
Mutants of the membrane-binding region of Semliki Forest virus E2 protein. Topology and membrane binding
Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis
Mutants paramyxovirus SV5 fusion protein - regulated extensive syncytium structure
Mutants ubiquinol-cytochrome c2 oxidoreductase tolerant Qo site inhibitors - consequences ubiquinone ubiquinol affinity catalysis
Mutants yeast Saccharomyces cerevisiae producing big amounts flavor components isobutyl alcohol isoamyl alcohol
Mutants with Temperature-Sensitive Defects in the Escherichia coli Mismatch Repair System: Sensitivity to Mispairs Generated In Vivo
Mutants with altered Ca2+-channel properties in Paramecium tetraurelia: isolation, characterization and genetic analysis
Mutants hydrophobic area simian virus 40 big tumor antigen defective binding cellular protein p53
Mutants with defective phosphatase activity show no phosphorylation-dependent oligomerization of CheZ. The phosphatase of bacterial chemotaxis
Mutants, Suppressors, and Wrinkled Colonies: Mutant Alleles of the Cell Division Gene ftsQ Point to Functional Domains in FtsQ and a Role for Domain 1C of FtsA in Divisome Assembly
Mutasynthesis of siderophore analogues by Pseudomonas aeruginosa
Mutated Form of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Interacts with the Homologous Fusion Protein despite Deficiencies in both Receptor Recognition and Fusion Promotion
Mutated barley (1,3)-b- D-glucan endohydrolases synthesize crystalline (1,3)-b- D-glucans
Mutated recombinant human heavy-chain ferritins and myelosuppression in vitro and in vivo: a link between ferritin ferroxidase activity and biological function
Mutated-c-actin restores growth yeast amino acid transport defective mutant
Mutating Critical Lysine ShK Toxin Alters Its Binding Configuration Pore- Vestibule Region Voltage-Gated Potassium Channel, Kv1.3
Mutating protein kinase cAMP-binding sites into cGMP-binding sites. Mechanism of cGMP selectivity
Mutating the primer grip of p66 HIV-1 reverse transcriptase implicates tryptophan-229 in template-primer utilization
Mutation Accumulation Affects Male Virility Drosophila Selected Later Reproduction
Mutation Ala2- >Ser destabilizes intersubunit interactions molecular chaperone GroEL
Mutation Analysis of the Aggrecan Gene in Chickens with Tibial Dyschondroplasia
Mutation Analysis of the Functional Role of Amino Acid Residues in Domain IV of Elongation Factor G
Mutation Analysis of the Histidine Residues in the Glycylglycine Endopeptidase ALE-1
Mutation E252C Increases Drastically the Km Value for Na+ and Causes an Alkaline Shift of the pH Dependence of NhaA Na+/H+ Antiporter of Escherichia coli
Mutation History of the Roma/Gypsies
Mutation Lys758- >Ile of the sarcoplasmic reticulum Ca2+-ATPase enhances dephosphorylation of E2P and inhibits the P2 to E1Ca2 transition
Mutation Patterns and Structural Correlates in Human Immunodeficiency Virus Type 1 Protease following Different Protease Inhibitor Treatments
Mutation Patterns of Mitochondrial H- and L-Strand DNA in Closely Related Cyprinid Fishes
Mutation Rate Variation at Human Dinucleotide Microsatellites
Mutation Rate and Predicted Phenotypic Target Sizes in Ethylnitrosourea-Treated Mice
Mutation Rates, Spectra and Hotspots in Mismatch Repair-Deficient Caenorhabditis elegans
Mutation T318M in the CYP11B2 gene encoding P450c11AS (aldosterone synthase) causes corticosterone methyl oxidase II deficiency
Mutation affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae
Mutation affecting germination Myxococcus xanthus
Mutation affecting resistance Escherichia coli K12 nalidixic acid
Mutation examination BRCA2 gene primary breast cancers
Mutation analysis of Lhca1 antenna complex: Low energy absorption forms originate from pigment-pigment interactions
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys574, the active site Glu240, and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells
Mutation examination metallo-b-lactamase CcrA Bacteroides fragilis
Mutation analysis of the cystic fibrosis transmembrane regulator gene in Native American populations of the Southwest
Mutation analysis of very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) deficiency: identification and characterization of mutant VLCAD cDNAs from four patients
Mutation and Evolution of Microsatellite Loci in Neurospora
Mutation adaptation - directed mutation controversy evolutionary perspective
Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor b antagonists
Mutation and cloning of eryG, the structural gene for erythromycin O-methyltransferase from Saccharopolyspora erythraea, and expression of eryG in Escherichia coli
Mutation evolution (book review)
Mutation and killing of Escherichia coli expressing a cloned Bacillus subtilis gene whose product alters DNA conformation
Mutation and selection during the secondary response to 2-phenyloxazolone
Mutation and the environment (book review)
Mutation at Residue 523 Creates a Second Receptor Binding Site on Human Parainfluenza Virus Type 1 Hemagglutinin-Neuraminidase Protein
Mutation amino acid position 133 H-2Dd prevents b2m association immune recognition surface expression
Mutation b-Tubulin Codon 200 Indicated Thiabendazole Resistance Penicillium digitatum Collected California Citrus Packinghouses
Mutation at histidine 338 of gp91phox9 depletes FAD and affects expression of cytochrome b558 of the human NADPH oxidase
Mutation Chlamydomonas nuclear NAC2 locus specifically affects stability chloroplast psbD transcript encoding polypeptide D2 PS II
Mutation at the Evi1 Locus in Junbo Mice Causes Susceptibility to Otitis Media
Mutation at the Exit Gate of the Salmonella Gyrase A Subunit Suppresses a Defect in the Gyrase B Subunit
Mutation Polymerase Active Site Mouse DNA Polymerase Increases Genomic Instability Accelerates Tumorigenesis
Mutation at the processing site of chicken low density lipoprotein receptor-related protein impaired efficient endoplasmic reticulum exit, but proteolytic cleavage is not essential for its endocytic functions
Mutation breeding (book review)
Mutation causing autosomal dominant nocturnal frontal lobe epilepsy alters Ca2+ permeability, conductance, and gating of human a4/b2 nicotinic acetylcholine receptors
Mutation causing overproduction of outer membrane protein OmpF and suppression of OmpC synthesis in Escherichia coli
Mutation causing reverse osmoregulation of synthesis of OmpF, a major outer membrane protein of Escherichia coli
Mutation creates an open reading frame within the 5 untranslated region of macaque erythrocyte carbonic anhydrase (CA) I mRNA that suppresses CA I expression and supports the scanning model for translation
Mutation creates an open reading frame within the 5' untranslated region of macaque erythrocyte carbonic anhydrase (CA) I mRNA that suppresses CA I expression and supports the scanning model for translation
Mutation detection pyrosequencing - sequencing exons 5-8 p53 tumor suppressor gene
Mutation detection in phenylketonuria by using chemical cleavage of mismatch: importance of using probes from both normal and patient samples
Mutation eliminating mitochondrial leader sequence of methylmalonyl-CoA mutase causes muto methylmalonic acidemia
Mutation in CUL4B, Which Encodes a Member of Cullin-RING Ubiquitin Ligase Complex, Causes X-Linked Mental Retardation
Mutation Cys662 Escherichia coli DNA topoisomerase I confers temperature sensitivity change DNA cleavage selectivity
Mutation in Escherichia coli under starvation conditions: a new pathway leading to small deletions in strains defective in mismatch correction
Mutation GLI3 postaxial polydactyly type A
Mutation in Mouse Hei10, an E3 Ubiquitin Ligase, Disrupts Meiotic Crossing Over
Mutation in NS2, a nonstructural protein in influenza A virus, extragenically causes aberrant replication and expression of the PA gene and leads to generation of defective interfering particles
Mutation Npps mouse model ossification posterior longitudinal ligament spine
Mutation in Pseudomonas aeruginosa causing simultaneous defects in penicillin-binding protein 5 and in enzyme activities of penicillin release and D-alanine carboxypeptidase
Mutation in Rab3 GTPase-Activating Protein (RAB3GAP) Noncatalytic Subunit in a Kindred with Martsolf Syndrome
Mutation in TRMU Related to Transfer RNA Modification Modulates the Phenotypic Expression of the Deafness-Associated Mitochondrial 12S Ribosomal RNA Mutations
Mutation DNA-binding protein reveals association DNA-methyltransferase activity 26,000-Da polypeptide frog virus 3-infected cells
Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta
Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
Mutation in a tesB-Like Hydroxyacyl-Coenzyme A-Specific Thioesterase Gene Causes Hyperproduction of Extracellular Polyhydroxyalkanoates by Alcanivorax borkumensis SK2
Mutation in and lack of expression of tyrosine-related protein-1 (TRP-1) in melanocytes from an individual with Brown oculocutaneous albinism: a new subtype of albinism classified as OCA3
Mutation in galactosemia
Mutation hepatocyte nuclear factor-1b gene (TCF2) MODY
Mutation in neurofilament transgene implicates RNA processing in the pathogenesis of neurodegenerative disease
Mutation in the AF-2/hormone-binding domain of the chimeric activator GAL4 estrogen receptor VP16 inhibit hormone-dependent transcriptional activation and chromatin remodeling in yeast
Mutation in the Auxiliary Calcium-Channel Subunit CACNA2D4 Causes Autosomal Recessive Cone Dystrophy
Mutation in the COL2A1 gene in a patient with hypochondrogenesis. Expression of mutated COL2A1 gene is accompanied by expression of genes for type I procollagen in chondrocytes
Mutation in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development
Mutation in the Trapa/Ssr1 Gene, Encoding Translocon-Associated Protein a, Results in Outflow Tract Morphogenetic Defects
Mutation VP1-LDV Motif Murine Polyomavirus Affects Viral Infectivity Conditions Virus Tissue Tropism vivo
Mutation in the a5(IV) collagen chain in juvenile-onset Alport syndrome without hearing loss or ocular lesions: detection by denaturing gradient gel electrophoresis of a PCR product
Mutation in the class II trans-activator leading to a mild immunodeficiency
Mutation in the gene encoding the a chain of platelet glycoprotein Ib in platelet-type von Willebrand disease
Mutation in the magnesium binding site of hMSH6 disables the hMutSa sliding clamp from translocating along DNA
Mutation nucleotide binding loop adenylate kinase Escherichia coli
Mutation in the phosphoribosylpyrophosphate synthetase gene (prs) that results in simultaneous requirements for purine and pyrimidine nucleosides, nicotinamide nucleotide, histidine, and tryptophan in Escherichia coli
Mutation in the primer binding site of type 1 human immunodeficiency virus genome affects virus production and infectivity
Mutation specificity polypeptide type I restriction endonuclease REcoK affects subunit assembly
Mutation in type II procollagen (COL2A1) that substitutes aspartate for glycine a1-67 and that causes cataracts and retinal detachment: evidence for molecular heterogeneity in the Wagner syndrome and the Stickler syndrome (arthro-ophthalmopathy)
Mutation stimulated vitro C-8 guanine aminofluorene template modified T7 DNA polymerase
Mutation modulating Raf signaling in Drosophila eye development
Mutation of 17Rn3 Shows That Odz4 Is Required for Mouse Gastrulation
Mutation 3 splice diverse class I genes results diverse utilization cryptic splice sites
Mutation of All Runx (AML1/Core) Sites in the Enhancer of T-Lymphomagenic SL3-3 Murine Leukemia Virus Unmasks a Significant Potential for Myeloid Leukemia Induction and Favors Enhancer Evolution toward Induction of Other Disease Patterns
Mutation of Amino Acids in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase That Contact the Template-Primer Affects RNase H Activity
Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation
Mutation of Arg-54 strongly influences heme composition and rate and directionality of electron transfer in Paracoccus denitrificans cytochrome c oxidase
Mutation of Arg273 to Leu alters the specificity of the yeast N-glycan processing class I a1,2-mannosidase
Mutation Arginine 228 Lysine Enhances Glucosyltransferase Activity Bovine b-1,4-Galactosyltransferase I
Mutation Arginine 357 CP43 Protein Photosystem II Severely Impairs Catalytic S-State Cycle H2O Oxidation Complex
Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation
Mutation Asparagine 52 Glycine Promotes Alkaline Form Iso-1-cytochrome Causes Loss Cooperativity Acid Unfolding
Mutation of B-Raf in Human Choroidal Melanoma Cells Mediates Cell Proliferation and Transformation through the MEK/ERK Pathway
Mutation of Bacillus firmus OF4 to duramycin resistance results in substantial replacement of membrane lipid phosphatidylethanolamine by its plasmalogen form
Mutation COOH-terminal lysines overexpressed aB-crystallin abrogates ischemic protection cardiomyocytes
Mutation of Capsid Protein Phosphorylation Sites Abolishes Cauliflower Mosaic Virus Infectivity
Mutation Conserved Charged Residues Mitochondrial TIM10 Subunits Precludes TIM10 Complex Assembly, Does Abolish Growth Yeast Cells
Mutation of CpGs in the Murine Stem Cell Virus Retroviral Vector Long Terminal Repeat Represses Silencing in Embryonic Stem Cells
Mutation of Critical GIRK Subunit Residues Disrupts N- and C-Termini Association and Channel Function
Mutation of Cys105 Inhibits Dimerization of p12CDK2-AP1 and Its Growth Suppressor Effect
Mutation of Cys672 allows recombinant expression of activatible macrophage-stimulating protein
Mutation of Glu-80- >Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex
Mutation of Glutamate 155 of the GABAA Receptor b2 Subunit Produces a Spontaneously Open Channel: A Trigger for Channel Activation
Mutation of Gly-94 in transmembrane segment M1 of Na+,K+-ATPase interferes with Na+ and K+ binding in E2P conformation
Mutation of Host dnaJ Homolog Inhibits Brome Mosaic Virus Negative-Strand RNA Synthesis
Mutation of Interfacial Residues Disrupts Subunit Folding and Particle Assembly of Physalis mottle tymovirus
Mutation of Leu-536 in Human Estrogen Receptor-a Alters the Coupling between Ligand Binding, Transcription Activation, and Receptor Conformation
Mutation of Leu25 and Val27 introduces CC chemokines activity into interleukin-8
Mutation PAX9 oligodontia
Mutation of RNA Pol III Subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and Disrupts Zebrafish Digestive Development
Mutation of SENP1/SuPr-2 Reveals an Essential Role for Desumoylation in Mouse Development
Mutation of Single Hydrophobic Residue I27, L35, F39, L58, L65, L67, or L71 in the N Terminus of VP5 Abolishes Interaction with the Scaffold Protein and Prevents Closure of Herpes Simplex Virus Type 1 Capsid Shells
Mutation of Threonine 766 in the Epidermal Growth Factor Receptor Reveals a Hotspot for Resistance Formation against Selective Tyrosine Kinase Inhibitors
Mutation Tn5 Transposase b-Loop Residues Affects All Steps Tn5 Transposition - The Role Conformational Changes Tn5 Transposition
Mutation of Tp53 contributes to the malignant phenotype of Abelson virus-transformed lymphoid cells
Mutation of Tyr235 in the NAD(H)-binding subunit of the proton-translocating nicotinamide nucleotide transhydrogenase of Rhodospirillum rubrum affects the conformational dynamics of a mobile loop and lowers the catalytic activity of the enzyme
Mutation of Tyrosine in the Conserved NPXXY Sequence Leads to Constitutive Phosphorylation and Internalization, but Not Signaling, of the Human B2 Bradykinin Receptor
Mutation of YMYL in the Nipah Virus Matrix Protein Abrogates Budding and Alters Subcellular Localization
Mutation Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase I DNA Topoisomerase I-dependent Poison
Mutation of a Conserved Asparagine in the I-like Domain Promotes Constitutively Active Integrins aLb2 and aIIbb3
Mutation of a Conserved Hydrophobic Patch Prevents Incorporation of ZP3 into the Zona Pellucida Surrounding Mouse Eggs
Mutation of a Conserved Threonine in the Third Transmembrane Helix of a- and b-Connexins Creates a Dominant-negative Closed Gap Junction Channel
Mutation Conserved Tryptophan Chitin-Binding Cleft Serratia marcescens Chitinase A Enhances Transglycosylation
Mutation of a Critical Arginine in the GTP-binding Site of Transglutaminase 2 Disinhibits Intracellular Cross-linking Activity
Mutation of a Dibasic Amino Acid Motif Within the C Terminus of the P2X7 Nucleotide Receptor Results in Trafficking Defects and Impaired Function
Mutation Lysine Residue Homeodomain Generates Dominant Negative Thyroid Transcription Factor 1
Mutation Nitrate Transporter, AtNRT1:4, Results Reduced Petiole Nitrate Content Altered Leaf Progress
Mutation of a Novel Gene Results in Abnormal Development of Spermatid Flagella, Loss of Intermale Aggression and Reduced Body Fat in Mice
Mutation of a Nuclear Respiratory Factor 2 Binding Site in the 5 Untranslated Region of the ADSL Gene in Three Patients with Adenylosuccinate Lyase Deficiency
Mutation of a Single Amino Acid Residue in the Basic Region of