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Education

Top > Society > Biotechnology > DNA Testing > Education



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Introductory page to forensic DNA-typing for attorneys, first published in 1997. Glossary, with update on evaluating evidence for reanalysis, from a consultant in Berkeley, CA.
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Test to see if the student has grasped the relative costs in laboratory testing of blood samples, for the economical elimination and final identification of suspects, from SWBIC, New Mexico State University, Las Cruces, NM.
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DNA Typing: RFLP and PCR-based Systems, forensic and research applications, course class workshop
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The Forensic specialty concentrates on QA and bioinformatics in forensic analysis of DNA data from biological materials by Department of Chemistry, University of Central Florida, Orlando, FL.
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DNA Interactive is an educational web site resource that
celebrates the 50th anniversary of the discovery of the DNA double helix structure. There are six
sections to this web site: Timeline, Code, Manipulation, Genome, Applications, Implications.
Each section is split into modules and has rare video interviews with scientists, 3D animations,
and narrative text to present and explain DNA science.
Timeline is an interactive, animated exploration of genetics and molecular biology from Gregor Mendel
and early genetics to Mario Capecchi, Francis Collins and current biotechnological techniques and
events. In the Timeline section, site visitors can travel through time to chart the history of
DNA science.
Code/Finding the Structure is the story of DNA: the discovery of its 3D structure, the double
helix, by James Watson and Francis Crick and the scientific clues provided by others like Rosalind
Franklin, Maurice Wilkins, Erwin Chargaff and Linus Pauling. Code/Copying the Code explains how
DNA works to make RNA to make protein. A number of scientists including Sydney Brenner, Matthew
Meselson, and Francois Jacob worked on the Central Dogma proposed by Watson and Crick.
Code/Reading the Code explains how the genetic code was broken through work done by Marshall
Nirenberg, Sydney Brenner, Gobind Khorana, Paul Berg, Maxine Singer. Code/Controlling the Code
explains the lac operon system first discovered by Francois Jacob and Jacques Monod, and DNA
folding or DNA packaging.
In the Manipulation section, visitors can discover the DNA science that transformed genetics and
biology. Manipulation/Revolution tells the story of how scientists struggled to isolate and study genes, and how they learned to cut, paste, and copy DNA. This section focuses on the work of Werner Arber, Arthur Kornberg, James Watson, Paul Berg, Herbert Boyer, and Stanley Cohen. Furthermore, the Revolution module explores the controversy that surrounded the first recombinant DNA (rDNA) experiments that culminated in the Asilomar conference of 1975, including reflections by participants such as Sydney Brenner, Robert Pollack, Victor McElheny, and Alexnder Capron. Manipulation/Techniques
explains methods for manipulating DNA including cutting and pasting, transferring and storing,
large-scale analysis, sorting and sequencing, amplifying DNA using the polymerase chain reaction
(PCR) method developed by Kary Mullis, and model organisms. The Manipulation/Production module
explains how recombinant DNA technology was used to make insulin, and highlights the work of
Herbert Boyer, David Goeddel, and Walter Gilbert.
Genome offers an exploration of ?the book of life? and the information contained within.
Genome/Tour features both an overview and a close-up of a chromosome, and covers the technique of
fluorescence in situ hybridization that highlights chromosomal structures such as centromeres and
telomeres. Genome/Project is the story of the Human Genome Project, the international effort to
map and sequence all human genes, and features interviews with Robert Sinsheimer, Eric Lander,
James Watson, Francis Collins, David Botstein, Jim Kent, John Sulston, J. Craig Venter, and
President William Clinton. Genome/Genome mining presents an introduction to the burgeoning field
of bioinformatics that integrated biology and computer science. This module features Gene Boy,
a unique educational tool to analyze DNA sequences.
Applications is an investigation into the many uses of DNA science.
Applications/Human Identification focuses on the technique of DNA fingerprinting developed by
Alec Jeffreys and how it is used in forensic analysis. This module explores how DNA fingerprinting
has been used to prove kinship, guilt, and innocence, and features an in-depth look at the case
of Marvin Anderson, a wrongly-imprisoned man who was freed based on DNA analysis conducted by
the Innocence Project. Applications/Recovering the Romanovs focuses on the mystery of Anna
Anderson, who claimed to be Princess Anastasia, and how mitochondrial DNA evidence analyzed by
Michael Baden and Syd Mandelbaum proved her true identity. Applications/Genes and Medicine centers
on the promise of the Gene Age to improve the diagnosis and treatment of genetic diseases such as cancer.
This section covers the race to find and clone the cancer-associated gene BRCA1; the development and
impact of tests to detect mutations in BRCA1 and BRCA2; the new era of DNA exploration made possible
by DNA microarray and GeneChip? technology; the design of the drug Gleevec? to control chronic myeloid
leukemia; and the gene targeting techniques that give rise to the possibility of directly correcting
genetic defects. Genes and Medicine features interviews with Mary-Claire King, Mark Skolnick,
Barbara Weber, Pat Brown, Stephen Fodor, David Botstein, Brian Druker, and Mario Capecchi.
Details Hits: 1 Votes: 0 Ratings: Reviews: Google PR:

Shockwave presentation of early examples of use of DNA in the criminal, maternity and patenity cases, from Dolan Learning Center, Cold Spring Harbor, NY.
Details Hits: 2 Votes: 0 Ratings: Reviews: Google PR:



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