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Immunoblotting with the pooled sera of patients with melon allergy showed that melon allergens were unaffected by crude human saliva. However, the 13-kDa component (profilin) was digested in the SGF (Rodriguez et al.
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Cross-reactivity was observed with rBet v2 (birch pollen profilin) (Jensen-Jarolim et al. 1998) [913]. Like other profilin allergens Cap a 2 is involved in pollen-fruit IgE cross-reactivity.
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